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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

Fig. 7

Effects of MC3353 on E-cadherin and MMP2 mRNA expression levels in PC-3 and HCT116 cancer cells. Cells were treated with vehicle (DMSO or AcOH) used as control (CTR), MC3353 for 24 h, or 5-AZA or DAC for 5 days. a, b E-cadherin and c, d MMP2 transcripts quantification via qPCR in PC-3 and HCT116 cancer cells. Each histogram represents the mean of four independent experiments. Significance is represented as *p < 0.05 and as **p < 0.01 related to the control groups

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