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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

Fig. 6

Nuclear morphology analysis in U-937, RAJI, KG-1, and RPMI1788 cells. Cells were treated with increasing doses of MC3353. Upper panels—after 72 h of treatment, the nuclear morphology was analyzed by fluorescence microscopy after Hoechst and PI staining. Pictures are representative of three independent experiments. Lower panels—the results of cell counting are represented as the mean (± SD) of three independent experiments

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