Fig. 2
From: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
EGFP expression. MC3353 strongly demethylates pUCHL1 in human HCT116 colon cancer cells. Microscopy imaging (a–d) and FACS evaluation (e) of HCT116 cells transfected with a methylated pUCHL1 vector and treated for 5 days with DMSO as vehicle control (Ctr), 5-AZA, DAC, and MC3353 at indicated concentrations. The drugs were added every 2 days, and the medium was changed