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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

Fig. 2

EGFP expression. MC3353 strongly demethylates pUCHL1 in human HCT116 colon cancer cells. Microscopy imaging (ad) and FACS evaluation (e) of HCT116 cells transfected with a methylated pUCHL1 vector and treated for 5 days with DMSO as vehicle control (Ctr), 5-AZA, DAC, and MC3353 at indicated concentrations. The drugs were added every 2 days, and the medium was changed

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