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Table 3 Multiple linear regression showing the association between living in PM2.5 areas and AHRR (cg05575921) methylation

From: Methylation at cg05575921 of a smoking-related gene (AHRR) in non-smoking Taiwanese adults residing in areas with different PM2.5 concentrations

Variable Model 1 Model 2
β P value β P value
Area (reference: Northern)
 North-Central − 0.00274 0.503 − 0.0028 0.947
 Central − 0.01003 0.009 − 0.01069 0.009
 Southern − 0.01480 < .001 − 0.01487 < .001
P trend < .001   < .001  
Sex (reference: women)     
 Men − 0.01491 < .001 − 0.01413 < .001
Age − 0.00023 0.085 − 0.00022 0.114
Alcohol Drinking (reference: no)     
 Former − 0.01041 0.358 − 0.01497 0.238
 Current − 0.00532 0.475 − 0.00424 0.609
Exercise (reference: no)     
 Yes − 0.00199 0.490 − 0.00180 0.552
BMI − 0.00009 0.819 − 0.00005 0.906
SHS (reference: no)   
 Yes − 0.00119 0.796
  1. Model 1 included SHS in the analysis, model 2 excluded SHS from the analysis, SHS second-hand smoke