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Table 1 Clinical characteristics of the study subjects

From: Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

 

T2DM patients (n = 104)

Controls (n = 108)

p value

Age (years)

59.19 ± 11.88

57.59 ± 10.60

0.301a

Gender (male/female)

58/46

56/52

0.567b

Fasting blood glucose (mmol/L)

8.58 ± 0.49

4.81 ± 0.05

< 0.001a

Total cholesterol (TC, mmol/L)

4.47 ± 0.83

4.25 ± 0.52

0.028a

Triglyceride (TG, mmol/L)

2.31 ± 1.93

1.09 ± 0.32

< 0.001a

High-density lipoprotein cholesterol (HDL-C, mmol/L)

1.19 ± 0.33

1.53 ± 0.30

< 0.001a

Low-density lipoprotein cholesterol (LDL-C, mmol/L)

2.80 ± 0.80

2.57 ± 0.40

0.014a

Insulin (uU/mL)

10.12 ± 6.85

  

HbA1c (%)

8.56 ± 2.22

  

Vascular ultrasound

 With macrovascular diseases

68 (65.4%)

  

 Without macrovascular diseases

28 (26.9%)

  

 N/A

8 (7.7%)

  
  1. Data are presented as mean ± SD
  2. N/A not available
  3. aStudent’s t test
  4. bχ2 test