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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Fig. 4

The correlations cross SIRT6, TETs, glucose and the possible work model. a Correlation analysis between mRNA expression of SIRT6, TETs, and glucose in all human subjects (upper panel), OGTT (middle panel), and rats (lower panel). The correlation coefficients (r) (left panel) and p values (right panel) are shown. b The possible work model of DNA demethylation promoted by hyperglycemia via SIRT6 and TETs

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Clinical Epigenetics

ISSN: 1868-7083

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