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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Fig. 3

Upregulation of TETs and SIRT6 in both T2DM patients and diabetic rats. a The mRNA expression of TETs and SIRT6 in T2DM patients and controls. b–e The mRNA expression of TETs and SIRT6 at five different time points (0, 30, 60, 120, and 180 min) of OGTT. f The mRNA expression of TETs and SIRT6 in diabetic rats and controls. The mRNA expression levels were examined by qPCR and normalized to GAPDH and β-ACTIN, and data are expressed as the means ± SEM

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Clinical Epigenetics

ISSN: 1868-7083

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