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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Fig. 2

Dynamic 5mC and 5hmC mediated by glucose stimulation. The levels of a glucose, b 5mC, and c 5hmC at five different time points (0, 30, 60, 120, and 180 min) of OGTT from diabetes patients. The levels of d 5mC and e 5hmC at five different time points (0, 30, 60, 120, and 180 min) of OGTT from controls. f 5mC and g 5hmC contents in diabetic rats and controls. The contents of 5mC and 5hmC were detected by HPLC-MS/MS, and data are expressed as the means ± SD

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Clinical Epigenetics

ISSN: 1868-7083

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