Characteristics | Discovery cohort Project Viva N = 479 | Replication cohort Generation R Study N = 999 | ||
---|---|---|---|---|
Maternal | Mean (SD) or n (%) | |||
 Age, years | 32.1 (5.4) | 32.2 (4.3) | ||
 Pre-pregnancy BMI, kg/m2 | 24.7 (5.2) | 23.4 (3.9) | ||
 Antidepressant use | 14 (2.9%) | 14 (1.4%) | ||
 High anxiety | 40 (9.0%)a | 56 (5.8%)b | ||
 Depression mid-pregnancy | 33 (8.2%)a | 31 (3.2%)b | ||
 Race/ethnicity | ||||
 | Non-Hispanic White | 341 (71.2%) | Dutch | 931 (93.2%) |
 | Non-Hispanic Black | 56 (11.7%) | Non-Dutch Western | 63 (6.3%) |
 | Hispanic | 37 (7.7%) | Non-western | 5 (0.5%) |
 | Other | 45 (9.4%) | – |  |
 College graduate or more education | 317 (66.2%) | 669 (67.0%) | ||
 Smoking status | ||||
 | Never | 327 (68.3%) | Never during pregnancy | 772 (77.3%) |
 | Former | 100 (20.9%) | Quit when pregnancy was known | 93 (9.3%) |
 | During pregnancy | 52 (10.9%) | Continued during pregnancy | 134 (13.4%) |
Perinatal/infant | Mean (SD) or n (%) | |||
 Cesarean delivery | 79 (16.5%) | 103 (10.3%) | ||
 Gestational age at delivery, weeks | 39.8 (1.4) | 40.2 (1.4) | ||
 Birth weight-for-gestational age, z-score | 0.27 (1.0) | 0.26 (0.87)c | ||
 Female infant | 229 (47.8%) | 484 (48.4%) |