Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression

Table 5 Sensitivity and specificity of candidate gene methylation in classifying prostate tumor vs normal prostate tissue

Gene	Probe ID	Sensitivity	Specificity	AUC
ASB2	cg01956154	0.514	0.8	0.684
ASB2	cg19949550	0.759	0.8	0.834
ASB2	cg09247392	0.61	0.84	0.747
ETNK2	cg20136584	0.61	0.92	0.803
ETNK2	cg21535580	0.486	0.9	0.687
ETNK2	cg00103329	0.612	0.94	0.798
ETNK2	cg01566404	0.703	0.86	0.79
MEIS2	cg01958086	0.811	0.84	0.879
MEIS2	cg03951374	0.86	0.92	0.917
MEIS2	cg13800209	0.914	0.84	0.909
MEIS2	cg07433663	0.79	0.88	0.881
MEIS2	cg21643314	0.867	0.82	0.871
NRG1	cg04773818	0.794	0.9	0.849
NRG1	cg04555373	0.902	0.88	0.912
NRG1	cg03430846	0.888	0.86	0.891
NRG1	cg24946597	0.855	0.92	0.914
NRG1	cg00614182	0.862	0.84	0.881
NTN1	cg14615768	0.839	0.94	0.926
NTN1	cg17072465	0.481	0.94	0.671
NUDT10	cg21844331	0.381	0.86	0.62
NUDT10	cg22363867	0.755	0.7	0.747
NUDT10	cg15159291	0.341	0.86	0.61
NUDT10	cg00648125	0.558	0.84	0.712
NUDT10	cg02975846	0.558	0.88	0.705
NUDT10	cg20430749	0.311	1	0.558
NUDT10	cg06481089	0.306	0.92	0.603
NUDT10	cg09520583	0.5	0.92	0.75
SRPX	cg16626088	0.762	0.66	0.771
SRPX	cg14759284	0.818	0.92	0.902
SRPX	cg19736094	0.895	0.9	0.925
SRPX	cg17407511	0.874	0.9	0.909
SRPX	cg27485646	0.902	0.84	0.905
SRPX	cg03509565	0.8	0.92	0.905

ISSN: 1868-7083