Skip to main content

Advertisement

Table 3 Methylation frequency of two-gene panel (ADAMTS1 and/or BNC1) vs frequency of CA 19-9 elevation in different stages of pancreatic ductal adenocarcinoma

From: Promoter methylation of ADAMTS1 and BNC1 as potential biomarkers for early detection of pancreatic cancer in blood

Patients Stage I (%) Stage IIA (%) Stage IIB (%) Stages III–IV (%)
Positive/total Positive (%) Positive/total Positive (%) Positive/total Positive (%) Positive/total Positive (%)
ADAMTS1 7/8 87.5 7/9 77.8 18/20 90 2/2 100
BNC1 5/8 62.5 5/9 55.6 13/20 65 2/2 100
ADAMTS1 and/or BNC1 8/8 100 8/9 88.9 20/20 100 2/2 100
CA 19-9 (n = 34)* 4/7 57.1 4/9 44.4 11/17 64.7 0/1 0
ADAMTS1 and/or BNC1 + CA 19-9 8/8 100 8/9 88.9 20/20 100 2/2 100
  1. *Missing two CA 19-9 values, so % out of total recorded CA 19-9 values for each stage