Table 2 Methylation frequency of two-gene panel (ADAMTS1 and/or BNC1) vs frequency of CA 19-9 elevation in control, PDAC, and pancreatitis
Patients (n) | Control | PDAC | Pancreatitis | |||
|---|---|---|---|---|---|---|
Positive/total | Positive (%) | Positive/total | Positive (%) | Positive/total | Positive (%) | |
ADAMTS1 | 4/95 | 4.2 | 34/39 | 87.2 | 6/8 | 75 |
BNC1 | 6/95 | 6.3 | 25/39 | 65.1 | 4/8 | 50 |
ADAMTS1 and BNC1 | 2/95 | 2.1 | 21/39 | 53.8 | 3/8 | 37.5 |
ADAMTS1 and/or BNC1 | 8/95 | 8.0 | 38/39 | 97.4 | 7/8 | 87.5 |
CA 19-9 (n = 34) | N/A | 19/34 | 55.9 | N/A | ||
ADAMTS1 and BNC1 and CA 19-9* | N/A | 6/34 | 17.6 | N/A | ||
ADAMTS1 and/or BNC1 + CA 19-9 | N/A | 38/39 | 97.4 | N/A | ||