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Table 2 Methylation frequency of two-gene panel (ADAMTS1 and/or BNC1) vs frequency of CA 19-9 elevation in control, PDAC, and pancreatitis

From: Promoter methylation of ADAMTS1 and BNC1 as potential biomarkers for early detection of pancreatic cancer in blood

Patients (n) Control PDAC Pancreatitis
Positive/total Positive (%) Positive/total Positive (%) Positive/total Positive (%)
ADAMTS1 4/95 4.2 34/39 87.2 6/8 75
BNC1 6/95 6.3 25/39 65.1 4/8 50
ADAMTS1 and BNC1 2/95 2.1 21/39 53.8 3/8 37.5
ADAMTS1 and/or BNC1 8/95 8.0 38/39 97.4 7/8 87.5
CA 19-9 (n = 34) N/A 19/34 55.9 N/A
ADAMTS1 and BNC1 and CA 19-9* N/A 6/34 17.6 N/A
ADAMTS1 and/or BNC1 + CA 19-9 N/A 38/39 97.4 N/A
  1. *Positive for all three, N/A: Not applicable