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Table 1 Patient demographics, tumor clinicopathologic features

From: Promoter methylation of ADAMTS1 and BNC1 as potential biomarkers for early detection of pancreatic cancer in blood

 

Control (n = 95)

Cancer (n = 39)

p value (cancer vs control)

Pancreatitis (n = 8)

Average age, years (range)

65.5 (21–96)

60.1 (29–83)

0.059

46.6 (29–70)

Gender

 Male (%)

41 (43%)

26 (67%)

0.013

4 (50%)

 Female (%)

54 (57%)

13 (33%)

 

4 (50%)

Race

 White (%)

22 (23%)

34 (87%)

 

6 (78%)

 Black (%)

72 (76%)

2 (5%)

< 0.05

1 (11%)

 Others (%)

0 (0%)

3 (8%)

 

1 (11%)

 Not specified (%)

1 (1%)

0 (0%)

 

0 (0%)

CA 19-9 level*

–

n = 34

N/A

n = 1

 Average

–

665.3

–

 Median

–

47.6

–

 Highest

–

12,302.5

–

 Lowest

–

1

16.1

Smoking status

n = 95

n = 39

 

n = 8

 Never

38 (40%)

22 (56%)

 

5 (63%)

 Former

40 (42%)

10 (26%)

0.159

3 (38%)

 Current

16 (17%)

7 (18%)

 

0 (0%)

 Not specified

1 (1%)

0 (0%)

 

0 (0%)

Average tumor size (range, cm)**

–

3.2 (0.9–8)

N/A

–

Differentiation

 

n = 39

N/A

 

 Well

–

1 (3%)

–

 Moderate

–

17 (44%)

–

 Poor

–

12 (31%)

–

 Undifferentiated

–

2 (5%)

–

 Not specified

–

7 (18%)

–

  1. *CA 19-9: five values unavailable for PDAC patient and four unavailable for pancreatitis
  2. **Tumor size: three PDAC, no resection done, N/A: Not applicable