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Table 4 Most frequently altered methylated DMPs (the recurrent analysis)

From: Genome-wide methylation profiling of Beckwith-Wiedemann syndrome patients without molecular confirmation after routine diagnostics

Hypomethylated DMPs in DUSP22

 

MLID BWS1

BWS1

BWS2

BWS3

BWS11

BWS19

BWS22

Number of patients

cg07332563

7

cg21548813

7

cg03395511

7

cg15383120

7

cg18110333

7

cg05064044

7

cg11235426

7

cg01516881

7

cg26668828

7

cg01171360

7

Hypermethylated DMPs in protocadherin gamma gene cluster located on chromosome 5

 

MLID BWS1

MLID BWS2

MLID BWS3

MLID BWS4

BWS7

BWS24

BWS25

Number of patients

cg10933186

 

  

4

cg20717585

 

  

4

cg16574737

 

  

4

cg27079776

  

 

4

cg20433262

 

  

4

cg01418385

  

  

3

cg13725516

  

  

3

cg02580763

  

  

3

cg13972793

  

  

3

cg04160343

  

  

3

cg19928377

 

  

3

cg23985374

     

2

cg07242860

   

  

2

cg14472390

   

  

2

cg27553119

     

2

cg21537235

 

   

2

cg24120669

  

  

2

cg19689427

  

  

2

cg16579158

  

  

2

cg17760318

  

  

2

cg01301252

  

  

2

cg24996161

  

  

2

cg00978427

  

  

2

cg03086707

  

  

2

cg00633552

  

  

2

cg02022808

  

  

2

cg24633027

  

  

2

cg25564433

  

  

2

cg08292467

 

   

2

cg02742676

    

2

  1. statistically significant aberrant methylation