Skip to main content
Fig. 5 | Clinical Epigenetics

Fig. 5

From: Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

Fig. 5

An mQTL affecting gene expression of THNSL2 immediately adjacent to the DNAm probe. a Location of genes on chromosome 2 surrounding an eQTL for THNSL2 and nearby mQTL. The location of the eQTL gene expression probe is highlighted in purple, the mQTL DNAm probe is highlighted in orange and the mQTL and eQTL SNP is highlighted in green. The arrow indicates the association of the mQTL SNP with expression of the THNSL2 probe. b Expression of the THNSL2 probe (ILMN_2173294) in endometrium from women with different genotypes at rs6547758. c Methylation of the cg24977027 probe in endometrium from women with different genotypes at rs6547758. d SMR locus plot showing the endometrial eQTL P values of SNPs for the THNSL2 probe (ILMN_2173294) (top) and mQTL P values of SNPs from this study for the DNAm probe cg24977027 (bottom)

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us