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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival

Fig. 5

Differences in DLK1-MEG3 CpG site methylation and imprinted gene expression based in AML MNCs based on patient risk group and FLT3 mutation status. Kruskal-Wallis (a) or Mann-Whitney (c) analysis of methylation values for particular CpG site amplicons depending on AML patients’ risk groups (a) or presence of FLT3 mutation (c). WT, wild-type; Mut, mutated. Kruskal-Wallis (b) or Mann-Whitney (d) analysis of DLK1 and MEG3 and the DLK1/MEG3 expression ratio in MNCs from AML patients based on their risk group (b) or presence of FLT3 mutation (d). WT, wild-type; Mut, mutated

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Clinical Epigenetics

ISSN: 1868-7083

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