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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival

Fig. 4

Relationship between DLK1-MEG3 CpG site methylation and imprinted gene expression in AML MNCs. a Mann-Whitney analysis of DLK1 and MEG3 expression in AML MNCs based on the methylation values for particular CpG site amplicons. *p < 0.05. b Kruskal-Wallis test of DLK1 and MEG3 expression in AML MNCs based on the pooled CG6–CG9 or CG7 and CG9 amplicon median methylation results. Groups represent the number of CpG site amplicons out of 4 (CG6–9) or 2 (CG7 and CG9) analyzed which exhibited increased methylation relative to their respective median values

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Clinical Epigenetics

ISSN: 1868-7083

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