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Table 5 Detection rate (%) of SDC2 methylation in stool DNA from patients

From: Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA

Diagnosis

No. of samples

No. of SDC2 methylation detected (%)

Adenomas

44

12 (27.3)

  NA (< 1.0 cm)

41

10 (24.4)

  AA (≥ 1.0 cm)

3

2 (66.7)

  P valuea

0.360

 

CRC

245

221 (90.2)

  Sex

    Male

133

119 (89.5)

    Female

112

102 (91.1)

    P valuea

0.675

 

  Age

    ≤ 49

36

33 (91.7)

    50–59

62

54 (87.1)

    60–69

79

74 (93.7)

    ≥ 70

68

60 (88.2)

    P valuea

0.544

 

  Clinical stage

    0

3

3 (100)

    I

55

47 (85.5)

    II

70

64 (91.4)

    III

96

86 (89.6)

    IV

21

21 (100)

    P valueb

0.413

 

  Tumor location

    Ascending

34

28 (82.4)

    Transverse

11

8 (72.7)

    Descending

6

6 (100)

    Sigmoid

91

85 (93.4)

    Rectum

90

83 (92.2)

    Others

13

11 (84.6)

    P valueb

0.108

 

Gastric cancer

23

7 (30.4)

Liver cancer

10

3 (30.0)

  1. aP value was calculated by Chi-square test
  2. bP values were calculated by Fisher’s exact test