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Table 5 Detection rate (%) of SDC2 methylation in stool DNA from patients

From: Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA

Diagnosis No. of samples No. of SDC2 methylation detected (%)
Adenomas 44 12 (27.3)
  NA (< 1.0 cm) 41 10 (24.4)
  AA (≥ 1.0 cm) 3 2 (66.7)
  P valuea 0.360  
CRC 245 221 (90.2)
  Sex
    Male 133 119 (89.5)
    Female 112 102 (91.1)
    P valuea 0.675  
  Age
    ≤ 49 36 33 (91.7)
    50–59 62 54 (87.1)
    60–69 79 74 (93.7)
    ≥ 70 68 60 (88.2)
    P valuea 0.544  
  Clinical stage
    0 3 3 (100)
    I 55 47 (85.5)
    II 70 64 (91.4)
    III 96 86 (89.6)
    IV 21 21 (100)
    P valueb 0.413  
  Tumor location
    Ascending 34 28 (82.4)
    Transverse 11 8 (72.7)
    Descending 6 6 (100)
    Sigmoid 91 85 (93.4)
    Rectum 90 83 (92.2)
    Others 13 11 (84.6)
    P valueb 0.108  
Gastric cancer 23 7 (30.4)
Liver cancer 10 3 (30.0)
  1. aP value was calculated by Chi-square test
  2. bP values were calculated by Fisher’s exact test