From: Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA
Diagnosis | No. of samples | No. of SDC2 methylation detected (%) |
---|---|---|
Adenomas | 44 | 12 (27.3) |
  NA (< 1.0 cm) | 41 | 10 (24.4) |
  AA (≥ 1.0 cm) | 3 | 2 (66.7) |
  P valuea | 0.360 |  |
CRC | 245 | 221 (90.2) |
  Sex | ||
    Male | 133 | 119 (89.5) |
    Female | 112 | 102 (91.1) |
    P valuea | 0.675 |  |
  Age | ||
    ≤ 49 | 36 | 33 (91.7) |
    50–59 | 62 | 54 (87.1) |
    60–69 | 79 | 74 (93.7) |
    ≥ 70 | 68 | 60 (88.2) |
    P valuea | 0.544 |  |
  Clinical stage | ||
    0 | 3 | 3 (100) |
    I | 55 | 47 (85.5) |
    II | 70 | 64 (91.4) |
    III | 96 | 86 (89.6) |
    IV | 21 | 21 (100) |
    P valueb | 0.413 |  |
  Tumor location | ||
    Ascending | 34 | 28 (82.4) |
    Transverse | 11 | 8 (72.7) |
    Descending | 6 | 6 (100) |
    Sigmoid | 91 | 85 (93.4) |
    Rectum | 90 | 83 (92.2) |
    Others | 13 | 11 (84.6) |
    P valueb | 0.108 |  |
Gastric cancer | 23 | 7 (30.4) |
Liver cancer | 10 | 3 (30.0) |