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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine

Fig. 6

Features of the common epigenetic response. a Epigenetic transition gene sets. The individual sets are given together with their intersection (∩) and the numbers of genes belonging to them. b Heatmap of the Gene Set Z-scoring function (GSZ score) of modification for selected gene sets. These sets are enriched by genes contributing to the overexpression spots of the SOM calculated using the histone modification data (see Additional file 5). Entire sets are dominated by Set1 or Set2 genes (red arrows)

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