Skip to main content
Fig. 3 | Clinical Epigenetics

Fig. 3

From: Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine

Fig. 3

Characterization of gene-associated histone modification states. a The numbers of genes associated with a particular histone modification state (0/1-coded, sequence: H3K4me3 H3K27me3 H3K36me3) for both mouse genotypes. The states are ordered decreasingly according to their frequency in Msh2+/+ mice. The most frequent histone modification state of genes in Msh2+/+ and Msh2−/− mice are the modifications [100] and [101], respectively. The modifications [111] and [011] are rare in both genotypes in agreement with [53]. b Boxplots of the expression levels of genes associated with a particular histone modification state for a Msh2+/+ and a Msh2−/− mouse

Back to article page