From: Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults
Chra | Gene (distance to geneb) | DMRcate | comb-p | Minimum Pg | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Start (bpc) | End (bp) | FDRd | #CpGse | Start (bp) | End (bp) | Sidak Pf | #CpGs | |||
1 | RUNX3 | 25291041 | 25291905 | 0.005 | 7 (4) | 25291584 | 0.044 | 6 (3) | 0.001 | |
1 | RPS6KA1 | 26855423 | 26855926 | 0.006 | 4 (3) | 26855765 | 0.009 | 3 (3) | 9.1E-04 | |
1 | TFAP2E | 36038468 | 36039173 | 2.1E-04 | 8 (7) | 36038701 | 3.3E-04 | 6 (6) | 0.002 | |
1 | ARTN | 44398868 | 44399894 | 5.6E-04 | 10 (6) | 44399363 | 0.012 | 6 (4) | 9.8E-04 | |
1 | S100A12 h | 153347819 | 153348305 | 2.8E-04 | 2 (2) | 0.005 | 2.7E-06 | |||
1 | S100A14 | 153589528 | 153590243 | 0.013 | 4 (2) | 153589781 | 0.047 | 3 (2) | 0.001 | |
1 | S100A13 | 153599479 | 153600156 | 0.001 | 7 (6) | 6.6E-04 | 0.003 | |||
1 | ATP8B2 | 154300117 | 154300241 | 6.9E-04 | 2 (2) | 0.007 | 3.4E-05 | |||
1 | LAX1 | 203733971 | 203734559 | 0.004 | 6 (4) | 0.002 | 0.002 | |||
1 | C1orf35 | 228291118 | 228291705 | 0.023 | 6 (5) | 0.017 | 0.009 | |||
2 | ALS2CR11 | 202483704 | 202484583 | 0.007 | 10 (5) | 202484020 | 0.008 | 7 (5) | 0.006 | |
3 | AMT | 49459143 | 49460521 | 1.3E-06 | 10 (7) | 49459855 | 8.3E-05 | 9 (7) | 1.6E-04 | |
3 | PPM1L | 160475035 | 160475336 | 0.002 | 5 (5) | 0.003 | 0.002 | |||
3 | B3GALNT1 | 160822268 | 160822911 | 0.001 | 8 (5) | 160822711 | 0.031 | 5 (4) | 0.003 | |
5 | MGAT4B | 179230709 | 179231109 | 0.002 | 3 (2) | 0.006 | 2.5E-04 | |||
5 | OR2V1 (− 39,287) | 180511822 | 180512070 | 0.012 | 2 (2) | 0.020 | 7.8E-04 | |||
6 | DUSP22 | 291687 | 292823 | 7.6E-04 | 9 (8) | 291882 | 2.2E-04 | 8 (7) | 0.005 | |
6 | TRIM39 | 30297174 | 30297627 | 1.5E-06 | 11 (9) | 2.9E-05 | 6.7E-04 | |||
6 | LTA h | 31539539 | 31540750 | 1.9E-15 | 19 (11) | 31540461 | 4.5E-07 | 18 (11) | 3.5E-06 | |
6 | HLA-DMB | 32904074 | 32905190 | 1.2E-05 | 9 (5) | 32904621 | 0.001 | 5 (3) | 8.7E-06 | |
6 | HLA-DPB2 | 33083989 | 33085470 | 2.5E-06 | 22 (12) | 33084420 | 2.3E-04 | 21 (11) | 0.006 | |
6 | TRAF3IP2 | 111887243 | 111887834 | 0.002 | 2 (2) | 0.026 | 3.2E-04 | |||
6 | MLLT4; C6orf124 | 168227843 | 168228706 | 0.001 | 3 (3) | 168228374 | 0.004 | 2 (2) | 6.4E-05 | |
7 | UNCX (− 5426) | 1266180 | 1267228 | 8.2E-04 | 4 (4) | 1266616 | 0.001 | 3 (3) | 2.0E-04 | |
7 | EVX1 (− 2589) | 27279101 | 27279575 | 0.009 | 3 (2) | 0.044 | 1.8E-04 | |||
7 | STEAP2 | 89840396 | 89841435 | 1.9E-05 | 13 (5) | 89841214 | 0.004 | 12 (5) | 2.1E-04 | |
8 | CSGALNACT1 | 19459672 | 19460243 | 2.3E-05 | 7 (5) | 6.7E-05 | 1.4E-04 | |||
8 | KIAA0146; CEBPD (−19) | 48648112 | 48649767 | 7.6E-08 | 7 (7) | 48648813 | 3.9E-09 | 6 (6) | 7.4E-05 | |
8 | HEY1 | 80678770 | 80679314 | 0.002 | 4 (3) | 80678925 | 0.026 | 2 (2) | 4.4E-04 | |
8 | NDRG1 | 134307105 | 134307728 | 2.3E-05 | 3 (3) | 134307597 | 7.4E-04 | 2 (2) | 3.0E-05 | |
10 | HK1 | 71087924 | 71088038 | 0.009 | 2 (2) | 0.038 | 2.0E-04 | |||
10 | LRRC20 | 72141375 | 72141924 | 7.0E-06 | 5 (3) | 72141625 | 0.007 | 4 (3) | 1.2E-05 | |
10 | HTRA1 | 124254773 | 124254860 | 0.003 | 2 (2) | 0.010 | 1.1E-04 | |||
11 | IFITM3 (10863) | 330536 | 331179 | 5.1E-04 | 5 (3) | 0.001 | 1.2E-05 | |||
11 | LMO2 | 33913187 | 33914088 | 9.3E-04 | 5 (4) | 3.2E-04 | 7.2E-04 | |||
11 | ME3 (− 9563) | 86142104 | 86142587 | 5.1E-04 | 4 (3) | 0.012 | 1.0E-04 | |||
13 | PDX1 (− 1903) | 28491326 | 28492265 | 0.006 | 8 (3) | 28491409 | 28491975 | 0.035 | 6 (3) | 0.001 |
13 | PCDH20 | 61989203 | 61990025 | 6.0E-05 | 12 (8) | 61989701 | 5.3E-04 | 8 (7) | 6.7E-04 | |
13 | DAOA (−319,060) | 105791890 | 105792346 | 0.023 | 3 (3) | 0.024 | 0.003 | |||
14 | DAD1 (−58,286) | 22974144 | 22975521 | 0.007 | 6 (5) | 22974951 | 0.029 | 5 (4) | 1.2E-04 | |
14 | CTSG | 25045625 | 25046121 | 0.013 | 3 (3) | 0.008 | 0.002 | |||
14 | PLD4 h | 105390602 | 105391263 | 0.002 | 3 (2) | 105391018 | 0.007 | 2 (2) | 3.0E-06 | |
15 | GATM; LOC145663h | 45670068 | 45671708 | 8.3E-08 | 17 (7) | 45670478 | 45671347 | 1.2E-04 | 14 (7) | 6.4E-07 |
15 | TNFAIP8L3 | 51387571 | 51387921 | 0.002 | 5 (5) | 0.004 | 9.7E-04 | |||
15 | FLJ42289 | 100890441 | 100891257 | 8.3E-07 | 9 (4) | 100890907 | 1.0E-05 | 5 (4) | 3.3E-05 | |
16 | TMEM8A; LOC100134368 | 432973 | 434356 | 1.3E-05 | 7 (4) | 433439 | 433825 | 1.1E-04 | 5 (4) | 1.2E-04 |
16 | CLDN9 | 3062056 | 3062975 | 0.001 | 8 (6) | 3062349 | 8.0E-04 | 7 (6) | 0.005 | |
17 | ALOX12 | 6898738 | 6900356 | 6.9E-10 | 16 (12) | 6899888 | 1.9E-08 | 15 (12) | 0.001 | |
17 | WNK4 | 40932199 | 40932983 | 0.006 | 11 (6) | 40932746 | 0.005 | 9 (6) | 0.011 | |
17 | IGF2BP1 | 47091521 | 47092272 | 0.006 | 6 (5) | 47091978 | 0.042 | 5 (4) | 0.003 | |
17 | CCDC57 | 80084554 | 80085082 | 0.003 | 4 (4) | 0.001 | 0.002 | |||
19 | ELANE | 855536 | 856107 | 4.5E-04 | 4 (4) | 6.1E-05 | 2.8E-04 | |||
19 | FBXO17 | 39465821 | 39467258 | 2.0E-04 | 9 (6) | 39466757 | 6.1E-05 | 8 (6) | 0.003 | |
20 | C20orf123 | 45179157 | 45179413 | 0.002 | 6 (5) | 0.005 | 0.002 | |||
21 | RUNX1 | 36259067 | 36259797 | 0.005 | 5 (4) | 36259460 | 0.008 | 4 (4) | 0.003 | |
22 | PARVG | 44568337 | 44568812 | 0.024 | 9 (5) | 0.043 | 0.006 | |||
22 | PRR5 | 45125218 | 45126040 | 0.002 | 5 (4) | 45125666 | 0.005 | 4 (3) | 0.002 |