Association of recurrent venous thromboembolism and circulating microRNAs

Clinical Epigenetics

Table 3 Risk estimates for recurrent VTE based on single miRNA levels^a

miRNAs^b	OR	p value^c	95% CI
miR-15b-5p	7.8	0.003	2.1; 29.3
miR-106a-5p	0.37	0.004	0.19; 0.72
miR-197-3p	0.40	0.006	0.21; 0.77
miR-652-3p	0.40	0.009	0.20; 0.79
miR-361-5p	0.41	0.01	0.21; 0.83
miR-222-3p	2.4	0.02	1.18; 4.93
miR-26b-5p	1.96	0.03	1.08; 3.55
miR-532-5p	2.7	0.04	1.04; 7.05
miR-27b-3p	0.57	0.03	0.34; 0.96
miR-21-5p	1.91	0.04	1.05; 3.48
miR-103a-3p	0.45	0.02	0.22; 0.90
miR-30c-5p	1.75	0.04	1.03; 2.97
miR-146b-5p	1.56	0.053	0.99;2.44
miR-22-3p	0.58	0.07	0.32;1.05

^aΔCt = Ct_{global mean} − Ct_{miR of interest}
^bAll miRNAs were standardized (by standard deviation = SD). Odds ratios (ORs) are expressed per one SD increment. Only significant miRNAs (p value < 0.05) are shown
^cConditional logistic regression

ISSN: 1868-7083