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Table 2 Statistics and annotations for the top 22 CpGs with p < 1e−06

From: DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

CpG* HR1 SE Z score p value FDR* CHR* MAPINFO* Gene* Gene group* CpG island*
cg00154443 0.6695028 0.072733 − 5.51634 3.46E−08 0.008403 16 71917454 ATXN1L;ZNF821 Body;TSS200 N_Shore
cg03636200 1.1806664 0.030655 5.417627 6.04E−08 0.009774 17 80005395    N_Shelf
cg04157272 2.1306391 0.142672 5.301819 1.15E−07 0.013814 2 68017838    
cg03217572 1.4100455 0.065719 5.228685 1.71E−07 0.013814 7 142561918 EPHB6 Body  
cg01083884 1.7394170 0.106624 5.191615 2.08E−07 0.01446 13 113641411 MCF2L Body  
cg07202479 3.6623902 0.252289 5.145359 2.67E−07 0.014684 1 159174162 DARC TSS1500  
cg10741568 1.7502471 0.109628 5.105981 3.29E−07 0.014684 13 49546137    N_Shelf
cg27649037 1.2494070 0.043894 5.072916 3.92E−07 0.014684 8 53322510 ST18 TSS200  
cg16473125 0.6918957 0.072615 − 5.07224 3.93E−07 0.014684 16 55090720    Island
cg09049436 1.4448276 0.072928 5.045959 4.51E−07 0.014779 5 178854758    
cg14517004 1.5786783 0.090526 5.043703 4.57E−07 0.014779 22 48946660 FAM19A5 Body  
cg06654691 0.5845868 0.1069 − 5.02195 5.12E−07 0.015521 17 40825980 PLEKHH3 Body N_Shore
cg06936355 2.3773894 0.173358 4.995453 5.87E−07 0.015694 9 99213110 HABP4 Body Island
cg24860169 1.4223750 0.070717 4.98224 6.29E−07 0.015694 1 46924753    
cg22819488 0.6837794 0.076321 − 4.98058 6.34E−07 0.015694 3 28390286 AZI2;AZI2 1stExon;5′UTR Island
cg07552157 0.7664161 0.053454 − 4.97678 6.47E−07 0.015694 3 142720316 SR140 TSS200 Island
cg00003305 1.3086604 0.054424 4.94274 7.70E−07 0.016988 19 30715645    Island
cg04402350 1.3023196 0.053478 4.939353 7.84E−07 0.016988 4 146857565 ZNF827 Body Island
cg09724798 1.3792984 0.06519 4.932918 8.10E−07 0.016988 12 119741507 LOC144742 TSS1500  
cg16503753 0.5136465 0.135248 − 4.92589 8.40E−07 0.016988 14 64319245 SYNE2 TSS1500 N_Shore
cg01773858 1.4928783 0.081542 4.914106 8.92E−07 0.017321 11 73076892 ARHGEF17 Body S_Shelf
cg12145550 0.6807161 0.078476 − 4.90104 9.53E−07 0.017801 20 44600942 ZNF335 TSS200 Island
  1. 1Hazard ratio, compared to baseline hazard
  2. *Fields are gathered from the Illumina 450K BeadChip annotation file