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Table 2 Statistics and annotations for the top 22 CpGs with pā€‰<ā€‰1eāˆ’06

From: DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

CpG*

HR1

SE

Z score

p value

FDR*

CHR*

MAPINFO*

Gene*

Gene group*

CpG island*

cg00154443

0.6695028

0.072733

āˆ’ā€‰5.51634

3.46Eāˆ’08

0.008403

16

71917454

ATXN1L;ZNF821

Body;TSS200

N_Shore

cg03636200

1.1806664

0.030655

5.417627

6.04Eāˆ’08

0.009774

17

80005395

Ā Ā 

N_Shelf

cg04157272

2.1306391

0.142672

5.301819

1.15Eāˆ’07

0.013814

2

68017838

Ā Ā Ā 

cg03217572

1.4100455

0.065719

5.228685

1.71Eāˆ’07

0.013814

7

142561918

EPHB6

Body

Ā 

cg01083884

1.7394170

0.106624

5.191615

2.08Eāˆ’07

0.01446

13

113641411

MCF2L

Body

Ā 

cg07202479

3.6623902

0.252289

5.145359

2.67Eāˆ’07

0.014684

1

159174162

DARC

TSS1500

Ā 

cg10741568

1.7502471

0.109628

5.105981

3.29Eāˆ’07

0.014684

13

49546137

Ā Ā 

N_Shelf

cg27649037

1.2494070

0.043894

5.072916

3.92Eāˆ’07

0.014684

8

53322510

ST18

TSS200

Ā 

cg16473125

0.6918957

0.072615

āˆ’ā€‰5.07224

3.93Eāˆ’07

0.014684

16

55090720

Ā Ā 

Island

cg09049436

1.4448276

0.072928

5.045959

4.51Eāˆ’07

0.014779

5

178854758

Ā Ā Ā 

cg14517004

1.5786783

0.090526

5.043703

4.57Eāˆ’07

0.014779

22

48946660

FAM19A5

Body

Ā 

cg06654691

0.5845868

0.1069

āˆ’ā€‰5.02195

5.12Eāˆ’07

0.015521

17

40825980

PLEKHH3

Body

N_Shore

cg06936355

2.3773894

0.173358

4.995453

5.87Eāˆ’07

0.015694

9

99213110

HABP4

Body

Island

cg24860169

1.4223750

0.070717

4.98224

6.29Eāˆ’07

0.015694

1

46924753

Ā Ā Ā 

cg22819488

0.6837794

0.076321

āˆ’ā€‰4.98058

6.34Eāˆ’07

0.015694

3

28390286

AZI2;AZI2

1stExon;5ā€²UTR

Island

cg07552157

0.7664161

0.053454

āˆ’ā€‰4.97678

6.47Eāˆ’07

0.015694

3

142720316

SR140

TSS200

Island

cg00003305

1.3086604

0.054424

4.94274

7.70Eāˆ’07

0.016988

19

30715645

Ā Ā 

Island

cg04402350

1.3023196

0.053478

4.939353

7.84Eāˆ’07

0.016988

4

146857565

ZNF827

Body

Island

cg09724798

1.3792984

0.06519

4.932918

8.10Eāˆ’07

0.016988

12

119741507

LOC144742

TSS1500

Ā 

cg16503753

0.5136465

0.135248

āˆ’ā€‰4.92589

8.40Eāˆ’07

0.016988

14

64319245

SYNE2

TSS1500

N_Shore

cg01773858

1.4928783

0.081542

4.914106

8.92Eāˆ’07

0.017321

11

73076892

ARHGEF17

Body

S_Shelf

cg12145550

0.6807161

0.078476

āˆ’ā€‰4.90104

9.53Eāˆ’07

0.017801

20

44600942

ZNF335

TSS200

Island

  1. 1Hazard ratio, compared to baseline hazard
  2. *Fields are gathered from the Illumina 450K BeadChip annotation file
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Clinical Epigenetics

ISSN: 1868-7083

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