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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Epigenetic biomarker screening by FLIM-FRET for combination therapy in ER+ breast cancer

Fig. 1

FLIM-FRET screening identifies potential epigenetic treatment targets. a Schematic illustration of possible ERα-epigenetic biomarker association in a nucleosome scale that facilitates ER-regulated gene transcription. b Typical FLIM images show control (left) and FRET (right) results as lifetime reduces with distance between donor and acceptor fluorophores. c Schematic and prototype of biopsy tissue arrays subjected to FLIM analysis

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