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Table 4 Area under the curves and corresponding 95% confidential intervals predictive for 5-year overall survival†

From: Discovery and validation of DNA methylation markers for overall survival prognosis in patients with thymic epithelial tumors

 

AUC 95% CI

Crude P compared with Masaoka stage

Adjusted P value

Masaoka stage

0.742 (0.656–0.828)

  

cg05784862 KSR1†

0.941 (0.881–1.000)

7.63 × 10−6

1.526 × 10−5

cg07154254 ELF3†

0.940 (0.880–0.999)

7.50 × 10−6

2.249 × 10−5

cg02543462 IL1RN†

0.966 (0.923–1.000)

2.77 × 10−7

1.385 × 10−6

cg06288355 RAG1†

0.933 (0.869–0.996)

1.75 × 10−5

1.749 × 10−5

Risk score

1.000 (0.998–1.000)

6.75 × 10− 7

2.7 × 10−6

  1. †Masaoka stage was tested as binary variable (III–IV and I–II) and methylation status and risk score continuous variables