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Table 2 ZFP57 methylation in maternal blood pre- and post-intervention. DNA methylation levels of ZFP57 DMR in maternal blood samples at GW14 and GW36.

From: A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57

Sample group

Gestational week (GW)

Mean methylation (%)

Standard deviation (SD)

Change in methylation (%)

p values

Treatment

(n = 24)

GW14

57.47

15.37

+ 5.51

0.609

GW36

62.98

14.94

Placebo

(n = 24)

GW14

64.36

6.58

−1.51

0.826

GW36

62.85

7.13

  1. GW gestational week, SD standard deviation