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Table 9 Top 100 differentially methylated probes according to baseline anxiety (BAI)

From: Exploring the effect of antenatal depression treatment on children’s epigenetic profiles: findings from a pilot randomized controlled trial

CpG p Adjusted pa Gene Gene region ∆β
cg06513375 1.01E-06 0.77590274 ZNF251 Body − 0.106421132
cg19573881 5.11E-06 0.998778059    0.083994741
cg00117018 1.40E-05 0.998778059 ZNF251 Body − 0.13038673
cg11602361 3.18E-05 0.998778059 FYN 5′UTR − 0.045924181
cg21641920 3.80E-05 0.998778059 RBM33 Body − 0.056092107
cg13511253 4.12E-05 0.998778059 MAPK4 5′UTR − 0.06921116
cg11674381 4.68E-05 0.998778059    − 0.030888002
cg00115113 5.01E-05 0.998778059 LINC00483 Body 0.027732238
cg21918548 5.84E-05 0.998778059 ZNF251 Body − 0.100935223
cg01519784 5.87E-05 0.998778059    − 0.025857817
cg07081372 6.58E-05 0.998778059 TMX1 Body 0.020743268
cg26293081 7.19E-05 0.998778059 TNS3 Body 0.039738087
cg06626791 7.25E-05 0.998778059 CCNE2 5′UTR 0.012276869
cg04788249 7.26E-05 0.998778059 ATG7 5′UTR 0.003609404
cg08049441 7.76E-05 0.998778059 RPL32P3 Body − 0.024015531
cg10731606 8.45E-05 0.998778059 AGBL3 TSS200 0.031982023
cg02335517 0.000117192 0.998778059 IL6 Body − 0.013920705
cg12379948 0.00011944 0.998778059 WNT3 TSS1500 0.007283815
cg13242754 0.000127218 0.998778059 C14orf101 Body − 0.015166989
cg06245967 0.000130491 0.998778059 BANP 5′UTR − 0.029761211
cg21643916 0.000138817 0.998778059 PRKAR1B Body − 0.013338272
cg22500132 0.000147833 0.998778059 MUC1 TSS200 0.00823408
cg24555816 0.000150316 0.998778059    0.058918432
cg02893361 0.000160529 0.998778059 PIAS1 Body − 0.030954487
cg12906188 0.000164316 0.998778059 RGS4 Body 0.008487123
cg05524951 0.000170319 0.998778059    − 0.012679223
cg14122980 0.000170584 0.998778059 PTPRD 5′UTR − 0.023320139
cg13449967 0.000178787 0.998778059 ATG2A Body 0.029533776
cg17231980 0.000185655 0.998778059    − 0.013659095
cg04657000 0.000189668 0.998778059 FYN 5′UTR − 0.012205559
cg18612255 0.000205249 0.998778059    0.012801625
cg22063222 0.000229138 0.998778059    − 0.010538791
cg23760165 0.000231842 0.998778059 FADS2 TSS1500 0.00669263
cg24531534 0.000237063 0.998778059 LOXL2 Body 0.102423109
cg15745507 0.000240352 0.998778059    0.039058624
cg05731717 0.000243608 0.998778059    − 0.038853941
cg16888838 0.000245704 0.998778059 KIAA1549 3′UTR − 0.021553937
cg17190403 0.000249731 0.998778059 C6orf211 Body 0.029783554
cg18298090 0.000274478 0.998778059 ETV2 TSS1500 − 0.035320986
cg11341317 0.000285303 0.998778059    − 0.032941327
cg15264808 0.000285946 0.998778059 CENPN 5′UTR 0.012161477
cg21025551 0.000290064 0.998778059 ADRBK2 TSS200 0.008238703
cg15872329 0.000304128 0.998778059 BLOC1S2 Body 0.010747948
cg26594377 0.000311806 0.998778059 EFCAB11 5′UTR 0.007818559
cg27191554 0.000311819 0.998778059 NOTCH3 Body 0.016376385
cg25899954 0.000314492 0.998778059    − 0.015053877
cg09602803 0.000326585 0.998778059    0.052616473
cg23462514 0.000333695 0.998778059 RNF212 TSS200 − 0.085842379
cg18193440 0.000336288 0.998778059 TAF1L 1stExon 0.071586528
cg09398891 0.000343573 0.998778059    − 0.017821675
cg08949296 0.000351898 0.998778059 JPH1 1stExon 0.008914397
cg21943599 0.000355323 0.998778059 C1orf125 TSS1500 − 0.012630326
cg04322378 0.000356074 0.998778059 LINC01258 TSS200 0.036276539
cg13921204 0.000358982 0.998778059 SEC61A2 TSS200 0.004130793
cg07346187 0.000360053 0.998778059 ZC3H12D Body 0.008900888
cg11832804 0.000361177 0.998778059 TERT Body − 0.006660909
cg04899629 0.00036328 0.998778059 LOR2C3 TSS1500 − 0.067707778
cg01985858 0.000364399 0.998778059 OBFC2B TSS1500 0.012234912
cg03851648 0.000366413 0.998778059 PHC2 Body − 0.103038845
cg11102724 0.000382353 0.998778059    0.200746665
cg18570658 0.000387535 0.998778059 COL4A2 Body − 0.06295432
cg24942330 0.000389195 0.998778059 ASAH1 TSS1500 0.005198328
cg07571142 0.00039639 0.998778059 C10orf99 3′UTR − 0.022383608
cg14405643 0.000402335 0.998778059 IER5L 3′UTR 0.026828829
cg13147522 0.000402551 0.998778059 SAPS3 TSS200 0.011988911
cg15417944 0.000405638 0.998778059 RBM44 5′UTR − 0.03261725
cg00616952 0.000409576 0.998778059 SIPA1L3 Body − 0.019003771
cg23166923 0.000410512 0.998778059 PMPCA 1stExon 0.008004775
cg13297582 0.000411378 0.998778059 LDLRAD4 5′UTR − 0.092481987
cg00962271 0.000413861 0.998778059    − 0.042309368
cg11640106 0.000416865 0.998778059 LOC101929194 Body − 0.016168103
cg06981781 0.000418137 0.998778059 EGF Body − 0.011108508
cg24146773 0.000418853 0.998778059 SH3BGR 1stExon − 0.083744695
cg23579746 0.000438092 0.998778059 FCRLB TSS1500 − 0.026251069
cg09819772 0.000438692 0.998778059    − 0.019080858
cg06630983 0.000440009 0.998778059 PPM1F Body − 0.013620731
cg09207053 0.000444686 0.998778059 PCDHGA11 TSS200 0.021510517
cg11833983 0.000447858 0.998778059 KANSL2 Body − 0.020712784
cg05675803 0.000455891 0.998778059 C6orf52 Body 0.006716337
cg03265692 0.000455941 0.998778059 ATAD1 TSS1500 0.010548663
cg11463903 0.000458655 0.998778059 ING5 TSS1500 0.015381351
cg03211481 0.00046527 0.998778059 DNAJC1 Body − 0.022278955
cg17714799 0.000472182 0.998778059 CASP6 TSS1500 0.018907097
cg20034712 0.000482406 0.998778059 ZNF836 TSS1500 − 0.060359087
cg11554391 0.000485943 0.998778059 AHRR Body 0.014764295
cg06166863 0.000490293 0.998778059 PNN TSS200 0.007284371
cg26321013 0.000491445 0.998778059 WIPF2 1stExon 0.018566869
cg16261619 0.000495054 0.998778059 ZPBP TSS200 − 0.049720147
cg06871884 0.000495095 0.998778059 LINC00963 Body 0.008107368
cg16333300 0.000496236 0.998778059 TECTA Body − 0.023279226
cg21848211 0.000497682 0.998778059    − 0.019228316
cg16287252 0.00050262 0.998778059 GLT1D1 Body − 0.059937553
cg15568778 0.000504593 0.998778059    − 0.009418856
cg15247039 0.000514355 0.998778059    − 0.026521804
cg04800443 0.000518233 0.998778059    0.034208928
cg12937337 0.000519654 0.998778059 PTEN 5′UTR − 0.020668502
cg05308125 0.000534128 0.998778059    − 0.017025401
cg13267264 0.000538758 0.998778059 PRDM14 TSS200 0.023761421
cg06610641 0.000538794 0.998778059 ZNF527 TSS1500 0.019166156
cg16642284 0.00053992 0.998778059 FOXI2 TSS200 0.019871733
  1. ∆β = mean β (severely anxious) − mean β (mildly anxious)
  2. TSS transcription start site, UTR untranslated region
  3. aAdjusted for multiple testing [46]