Table 3 Top 100 differentially methylated probes according to intervention

cg19908420

3.40E-06

0.999997557

0.049137862

cg15495292

4.01E-06

0.999997557

AIG1

Body

0.079710136

cg05155812

1.56E-05

0.999997557

SUN1

TSS1500

− 0.280713404

cg18818484

2.20E-05

0.999997557

PTCHD2

0.022078691

cg17622532

2.21E-05

0.999997557

0.024836631

cg14034519

2.27E-05

0.999997557

SNX1

Body

0.053471841

cg26436424

3.24E-05

0.999997557

NGEF

Body

0.033261363

cg21494953

3.48E-05

0.999997557

C5orf23

TSS1500

0.036133838

cg19232929

3.58E-05

0.999997557

0.054387673

cg22342380

3.86E-05

0.999997557

0.03688025

cg13719771

5.98E-05

0.999997557

NDUFA9

Body

0.13765872

cg10356363

6.06E-05

0.999997557

CEBPB

TSS1500

0.026639222

cg05205351

6.20E-05

0.999997557

NOP56

Body

0.05930508

cg14231326

6.23E-05

0.999997557

0.031289864

cg14358699

7.14E-05

0.999997557

0.047991502

cg06961812

8.01E-05

0.999997557

PRODH2

Body

0.058582642

cg16007230

8.39E-05

0.999997557

ABCC3

ExonBnd

0.036161879

cg25968469

8.53E-05

0.999997557

ARHGAP22

Body

0.056699144

cg23619591

8.80E-05

0.999997557

C19orf81

Body

0.057592082

cg09240747

0.000101189

0.999997557

0.067301777

cg18077049

0.000101567

0.999997557

GLRA3

Body

0.116790545

cg24435401

0.000110721

0.999997557

NPAS4

TSS1500

0.021387283

cg23274420

0.000110944

0.999997557

0.068615769

cg09223928

0.000111509

0.999997557

0.030359585

cg18666104

0.000115314

0.999997557

CORO1C

Body

0.058415174

cg16273469

0.000115391

0.999997557

0.036049214

cg00541777

0.000120288

0.999997557

COLEC11

TSS1500

0.120518141

cg06646082

0.0001208

0.999997557

BTBD17

TSS1500

0.0430183

cg03711840

0.000127893

0.999997557

PLXNA1

Body

0.043191584

cg19465002

0.000130791

0.999997557

0.033852961

cg14687471

0.000134464

0.999997557

NBR2

Body

0.023128809

cg27243560

0.000134814

0.999997557

0.031689225

cg05510714

0.000135017

0.999997557

KYNU

Body

0.153887531

cg12987887

0.000136898

0.999997557

UPB1

ExonBnd

− 0.01972518

cg26836955

0.000138572

0.999997557

LONP1

Body

0.039104166

cg26330841

0.000138665

0.999997557

0.032962344

cg16720807

0.000142967

0.999997557

FAM176A

5′UTR

0.042119403

cg01440210

0.000143289

0.999997557

0.030341728

cg17068417

0.000144326

0.999997557

EEFSEC

Body

0.030665165

cg15313810

0.000144443

0.999997557

ST6GALNAC4

Body

0.029787439

cg07545731

0.000147518

0.999997557

COL22A1

Body

0.04468122

cg14684297

0.000150469

0.999997557

ARHGAP33

5′UTR

0.032019831

cg10727673

0.000154265

0.999997557

TMEM22

TSS1500

0.089444195

cg04798314

0.000155738

0.999997557

SMYD3

Body

0.323390033

cg11035122

0.000160944

0.999997557

MIR758

TSS1500

0.055539324

cg12360330

0.000168181

0.999997557

CENPJ

Body

0.032193572

cg07469546

0.000172234

0.999997557

0.014405304

cg17785398

0.000172977

0.999997557

KCNJ6

Body

0.022656857

cg18291664

0.000173083

0.999997557

PRKAR1B

Body

0.040654976

cg09319487

0.000181803

0.999997557

0.033053753

cg11510586

0.000186082

0.999997557

0.107251714

cg25441526

0.000188457

0.999997557

WDFY4

Body

0.025251026

cg19379103

0.000188787

0.999997557

SSBP3

Body

0.031870653

cg19769811

0.00019183

0.999997557

RASGRF2

TSS1500

0.046395706

cg26221509

0.000199233

0.999997557

SCUBE1

Body

0.039685931

cg14700416

0.000199451

0.999997557

SPOCK3

5′UTR

0.049430209

cg22746421

0.000200331

0.999997557

0.02669027

cg23553242

0.000200938

0.999997557

USP2

Body

0.043740484

cg06617093

0.000206244

0.999997557

0.032231234

cg08670534

0.000206305

0.999997557

COL2A1

Body

0.032117847

cg15791944

0.000212127

0.999997557

0.055152706

cg17562896

0.000216404

0.999997557

SV2C

Body

0.037479302

cg02018176

0.000217297

0.999997557

KIAA1530

Body

0.047057842

cg11576176

0.000220243

0.999997557

GSX2

1stExon

0.03556139

cg09480336

0.0002295

0.999997557

POLD1

Body

0.03212232

cg21592262

0.000233681

0.999997557

0.06371313

cg12472342

0.000234117

0.999997557

− 0.069235248

cg18361948

0.00023564

0.999997557

0.029932491

cg00945089

0.000236572

0.999997557

GFRA1

Body

0.033266209

cg07442357

0.000238546

0.999997557

0.01892614

cg09193498

0.000239232

0.999997557

SEZ6

Body

0.042776024

cg02438610

0.000240811

0.999997557

SUN1

TSS1500

− 0.013139753

cg15037661

0.00024103

0.999997557

NR1D2

TSS1500

0.00946764

cg26264656

0.000243011

0.999997557

SKI

Body

0.034797294

cg24367840

0.000243465

0.999997557

PSMD14

Body

0.057487682

cg05289897

0.000259274

0.999997557

0.012403078

cg16419764

0.000261486

0.999997557

CDYL

Body

0.026043028

cg00248302

0.000266776

0.999997557

FCRL5

Body

0.028022889

cg24900542

0.000269678

0.999997557

0.085875055

cg15078841

0.000272298

0.999997557

0.022837528

cg12541879

0.000282436

0.999997557

PTPRN2

Body

0.056208383

cg01976641

0.000283246

0.999997557

0.05497368

cg17121322

0.000286514

0.999997557

0.025193249

cg17547875

0.000288231

0.999997557

0.01236688

cg18169610

0.000296554

0.999997557

CD81

Body

0.038708

cg04801704

0.000304651

0.999997557

TLL2

Body

0.025096532

cg23425290

0.000307508

0.999997557

ABCC1

Body

0.023343856

cg22680931

0.00030882

0.999997557

TMEM167B

TSS1500

0.122894387

cg01723825

0.000310423

0.999997557

URI1

TSS200

0.039217642

cg16261251

0.000311941

0.999997557

0.06722457

cg01400541

0.000314878

0.999997557

C10orf128

Body

0.042719378

cg26796807

0.000318004

0.999997557

0.04717045

cg10038145

0.000319876

0.999997557

POR

Body

0.045738894

cg09078103

0.000320468

0.999997557

SNX9

Body

0.027261168

cg08880699

0.000322485

0.999997557

0.043133838

cg03116452

0.00032398

0.999997557

PLD3

5′UTR

0.034421382

cg03071994

0.000324145

0.999997557

NR4A1

Body

0.029626215

cg21485062

0.000324634

0.999997557

C7orf25

Body

0.024308813

cg11504793

0.000326763

0.999997557

NOL4L

Body

0.025196146

cg04837576

0.00032871

0.999997557

ADRBK2

Body

0.030823149