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Table 11 Probes in candidate gene analysis showing differential methylation according to baseline depression (BDI-II) at uncorrected p < 0.01

From: Exploring the effect of antenatal depression treatment on children’s epigenetic profiles: findings from a pilot randomized controlled trial

CpG

p

Adjusted pa

Gene

Gene region

∆β

cg17578833

0.002812934

0.985858571

CRH

TSS1500

− 0.055448723

cg04137760

0.00427371

0.985858571

FKBP5

5′UTR

− 0.028541521

cg08077673

0.007257559

0.985858571

MEST

5′UTR

0.008859633

cg07583420

0.00759847

0.985858571

IGF2

Body

0.00580552

cg13167664

0.009158888

0.985858571

IGF2

Body

0.003859675

  1. ∆β = mean β (severely depressed) − mean β (mildly depressed)
  2. TSS transcription start site, UTR untranslated region
  3. aAdjusted for multiple testing [45]
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Clinical Epigenetics

ISSN: 1868-7083

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