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Table 10 Differential methylation of candidate genes according to baseline depression (BDI-II)

From: Exploring the effect of antenatal depression treatment on children’s epigenetic profiles: findings from a pilot randomized controlled trial

Gene ∆β 95% CI p
NR3C1 0.002 − 0.006 to 0.011 0.647
NR3C1 Promoter 0.006 − 0.005 to 0.020 0.2093
SLC6A4 0.004 − 0.022 to 0.028 0.647
OXTR 0.003 − 0.009 to 0.010 0.5123
NR3C2 − 0.002 − 0.012 to 0.007 0.647
MEST 0.009 − 0.002 to 0.018 0.1264
MEG3 0.007 − 0.008 to 0.0120 0.2921
IFG2 − 0.006 − 0.035 to 0.018 0.6005
HSD11B1 − 0.002 − 0.022 to 0.017 0.7938
HSD11B2 0.004 − 0.005 to 0.009 0.2093
H19 0.016 − 0.011 to 0.039 0.2624
CRHR1 0.008 − 0.016 to 0.0221 0.3575
CRHR2 0.005 − 0.014 to 0.0246 0.647
CRHRBP 0.011 − 0.0262 to 0.0372 0.5556
CRH − 0.006 − 0.017 to 0.009 0.3237
BDNF 0.003 − 0.001 to 0.010 0.1641
FKBP5 0.003 − 0.023 to 0.031 0.7414
  1. ∆β = mean β (severely depressed) − mean β (mildly depressed)