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Table 1 Baseline characteristics of all participants in a trial evaluating an antenatal cognitive behavioral therapy (CBT) versus treatment as usual (TAU), those that responded, and those that did not respond to the 5-year follow-up

From: Exploring the effect of antenatal depression treatment on children’s epigenetic profiles: findings from a pilot randomized controlled trial

 

All participants

Not participating in 5-year follow-up

Participating in 5-year follow-up

Baseline demographics

CBT (n = 28)

TAU (n = 26)

CBT (n = 16)

TAU (n = 15)

CBT (n = 12)

TAU (n = 11)

Mean (SD) BDI pre-treatment score

30.8 (9.5)

30.5 (8.9)

31.6 (9.7)

31.2 (7.8)

29.6 (9.5)

29.5 (10.4)

Mean (SD) BAI pre-treatment score

22.8 (10.0)

21.2 (10.2)

25.4 (10.1)

22.8 (12.2)

19.2 (9.0)

19.3 (7.1)

Mean (SD) BDI post-treatment score

13.0 (9.8)

17.4 (9.8)

12.9 (10.1)

17.3 (10.8)

13.0 (10.0)

17.6 (9.0)

Mean (SD) BAI post-treatment score

10.6 (7.6)

16.7 (11.8)

9.6 (5.4)

17.6 (14.3)

11.6 (9.9)

15.3 (7.1)

Mean (SD) ∆ BDI score (post-treatment − pre-treatment)

− 18.6 (10.0)

− 13.2 (12.8)

− 20.4 (12.0)

− 14.5 (10.4)

− 16.6 (7.3)

− 11.5 (16.1)

Mean (SD) ∆ BAI score (post-treatment − pre-treatment)

− 11.2 (9.4)

− 4.3 (8.3)

− 14.5 (10.1)

− 5.0 (9.8)

− 7.5 (7.2)

− 3.1 (6.0)

Mean (SD) maternal age in years

32.9 (5.9)

31.0 (5.8)

32.2 (6.5)

29.2 (5.6)

33.7 (5.7)

33.6 (5.2)

Mean (SD) gestational age in weeks

19.9 (7.7)

21.0 (6.0)

21.2 (8.0)

22.6 (6.1)

18.3 (7.2)

19.0 (5.5)

Antidepressant use (%)

7.1

22.7

14.3

26.7

11.1

Marital status (%)

 - Married

57.7

65.2

46.7

69.2

72.7

60.0

 - De Facto

34.6

21.7

46.7

15.4

18.2

30.0

 - Separated

8.7

7.7

10.0

 - Single

7.7

4.3

6.7

7.7

9.1

Birth location (%)

 - Australia

73.1

82.6

66.7

84.6

81.8

80.0

 - Other

26.9

17.4

33.3

15.4

18.2

20.0

Income (%)

 - Up to $ 20,000

4.5

10.0

 - $ 20,001–$ 40,000

8.0

22.7

7.1

25.0

9.1

20.0

 - $ 40,001–$ 60,000

20.0

13.6

28.6

16.7

9.1

10.0

 - $ 60,001–$ 80,000

28.0

27.3

21.4

33.3

36.4

20.0

 - > $ 80,001

32.0

31.8

28.6

25.0

36.4

40.0

 - Do not wish to divulge

12.0

-

14.3

-

9.1

Highest level of education (%)

 - Did not finish school

3.8

12.0

6.7

21.4

 - High School

7.7

24.0

13.3

21.4

27.3

 - Certificate Level/Apprenticeship

23.1

4.0

33.3

9.1

9.1

 - Advanced Diploma

19.2

4.0

6.7

7.1

36.4

 - Bachelor degree

11.5

24.0

20.0

28.6

18.2

 - Graduate diploma/certificate

19.2

16.0

6.7

7.1

36.4

27.3

 - Postgraduate Degree

15.4

16.0

13.3

14.3

18.2

18.2