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Table 1 Characteristics of the young and older monozygotic and dizygotic individual twins participating into the current study

From: Leisure-time physical activity and DNA methylation age—a twin study

 

Young 20–25 years

MZ vs DZ difference

Older 55–70 years

MZ vs DZ difference

MZ

DZ

p value

MZ

DZ

p value

Chronological age (years)

22.7 (0.9)

22.4 (0.7)

0.005

61.4 (3.7)

62.1 (3.8)

0.29

DNAm age (predicted years)

22.2 (3.8)

21.3 (3.6)

0.015

61.2 (5.7)

62.6 (5.4)

0.096

Age acceleration (residuals)

0.29 (3.54)

− 0.40 (3.48)

0.065

− 0.02 (5.46)

0.65 (4.95)

0.35

Body mass index (kg/m2)

23.0 (3.5)

23.7 (4.3)

0.055

27.2 (5.0)

28.2 (4.7)

0.11

Women, n (%)

218 (65%)

142 (59%)

0.28

162 (66%)

44 (52%)

0.11

Never smokers, n (%)

177 (53%)

126 (52%)

0.001

117 (48%)

42 (50%)

0.95

Former smokers, n (%)

30 (9%)

17 (7%)

86 (35%)

29 (35%)

Current smokers, n (%)

101 (30%)

98 (40%)

41 (17%)

13 (15%)

  1. Values are means and standard deviations unless otherwise stated. MZ, monozygotic; DZ dizygotic. Differences between groups on continuous variables were tested on design corrected T-test for independent samples and chi-square test (sex, smoking)