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Table 1 Characteristics of the young and older monozygotic and dizygotic individual twins participating into the current study

From: Leisure-time physical activity and DNA methylation age—a twin study

  Young 20–25 years MZ vs DZ difference Older 55–70 years MZ vs DZ difference
MZ DZ p value MZ DZ p value
Chronological age (years) 22.7 (0.9) 22.4 (0.7) 0.005 61.4 (3.7) 62.1 (3.8) 0.29
DNAm age (predicted years) 22.2 (3.8) 21.3 (3.6) 0.015 61.2 (5.7) 62.6 (5.4) 0.096
Age acceleration (residuals) 0.29 (3.54) − 0.40 (3.48) 0.065 − 0.02 (5.46) 0.65 (4.95) 0.35
Body mass index (kg/m2) 23.0 (3.5) 23.7 (4.3) 0.055 27.2 (5.0) 28.2 (4.7) 0.11
Women, n (%) 218 (65%) 142 (59%) 0.28 162 (66%) 44 (52%) 0.11
Never smokers, n (%) 177 (53%) 126 (52%) 0.001 117 (48%) 42 (50%) 0.95
Former smokers, n (%) 30 (9%) 17 (7%) 86 (35%) 29 (35%)
Current smokers, n (%) 101 (30%) 98 (40%) 41 (17%) 13 (15%)
  1. Values are means and standard deviations unless otherwise stated. MZ, monozygotic; DZ dizygotic. Differences between groups on continuous variables were tested on design corrected T-test for independent samples and chi-square test (sex, smoking)