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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

Fig. 7

DNA methylation in the promoter region of the ADIPOR2 gene. a A schematic representation of the adiponectin receptor 2 gene (ADIPOR2), including the CpG islands in the promoter region. b The methylation pattern in the ADIPOR2 promoter on the fetal and maternal sides of third-trimester placental biopsies from the control group. c The % methylation level in the ADIPOR2 promoter region from third-trimester placenta. DNA was extracted from third-trimester placental biopsies (on the fetal and maternal sides) in the control and obese women. After bisulfite treatment, the methylation level was determined by pyrosequencing. The data are quoted as the mean ± SEM. **p < 0.01; ***p < 0.001 in a Friedman test. (a) Maternal side vs. fetal side. (b) The obese group vs. the control group

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Clinical Epigenetics

ISSN: 1868-7083

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