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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

Fig. 2

ADIPOR expression in human third-trimester placental tissue. a, b mRNA expression of ADIPOR1 and ADIPOR2. Total RNA was extracted from the fetal and maternal sides of third-trimester placenta in control and obese women, and then analyzed using RT-qPCR. The data are quoted as the mean ± SEM. *p < 0.05 in a Wilcoxon test. (a) Maternal side vs. fetal side. **p < 0.01 in a Mann-Whitney test. (b) The obese group vs. the control group. c ADIPOR1 and ADIPOR2 protein expression. Lysates of third-trimester placental biopsies from control and obese women were extracted and then subjected to Western blot analysis using an anti-ADIPOR1/R2 or anti-β-actin antibody, as described in the “Methods” section. The data are representative of five separate experiments and are quoted as the mean ± SEM. *p < 0.05 in a Student t test. (b) The obese group vs. the control group

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