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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Aberrant methylation of Pax3 gene and neural tube defects in association with exposure to polycyclic aromatic hydrocarbons

Fig. 3

The effects of BaP and vitamin E on Pax3 methylation in E10.5 mouse embryos. a Mean methylation level of promoter region (amplicon 1 and amplicon 2) and body region (amplicon 3) within Pax3. b–d Methylation level for specific CpG sites in promoter region (b, c) and body region (d) among control group, BaP-treated group and vitamin E co-supplementation group (n = 24–28). TSS1500, TSS200, 5′URT, and the 1st exon were defined as the promoter region of Pax3 gene in this study. The significance of differences was calculated using ANOVA. *P < 0.05, **P < 0.01, ***P < 0.001, compared with control group. VE vitamin E

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Clinical Epigenetics

ISSN: 1868-7083

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