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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin

Fig. 2

Downregulation of KDM6A and KDM6B sensitizes OS to cisplatin in vitro. a The viability of control and KDM6A or KDM6B-depleted 143B and HOS cells with or without cisplatin was tested by CCK-8 assay. b Colony formation of parental and KDM6A or KDM6B-depleted 143B and HOS cells with or without cisplatin. c The percentage of apoptotic cells among parental and KDM6A or KDM6B-depleted 143B and HOS cells with or without cisplatin was analyzed by flow cytometry. *P < 0.05, **P < 0.01

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