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Table 1 Patients with multiple extramedullary diseases

From: Distinct promoter methylation profile reveals spatial epigenetic heterogeneity in 2 myeloma patients with multifocal extramedullary relapses

Patient

Time (months)

Sample

Plasma cell (%)

SHP1

CDKN2A

CDH1

CD56

CXCR4

1

0

Diagnostic BM

10

–

–

–

–

–

26

Duodenal plasmacytoma

> 90

+

+

–

–

–

26

Chest wall plasmacytoma

100

+

+

+

–

–

26

Relapsed BM

1

+

+

–

–

–

2

0

Diagnostic BM

CD138 sorted cells

–

–

–

–

–

2

Extradural plasmacytoma

> 90

+

–

–

–

–

23

Relapsed BM

CD138 sorted cells

–

–

–

–

–

23

Peripheral blood

34

+

–

–

–

–

  1. Abbreviations: BM bone marrow; +, presence of methylation; −, absence of methylation