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Fig. 7 | Clinical Epigenetics

Fig. 7

From: DNA methylation and histone post-translational modification stability in post-mortem brain tissue

Fig. 7

Bar graphs showing the semiquantitative intensity scores (mean ± 95% confidence intervals; maximum 3) for all epigenetic modification antibodies used in neonatal pig neocortex. DNA cytosine modifications, total histone H4, all histone methylation PTMs, H3K14ac, and H4K5ac and showed stable immunoreactivity up to 72 h post-mortem. H3K9ac was stable up to 48 h post-mortem. Total histone H3, H3K27ac, H4K12ac, and H4K16ac all showed a significant decline by 48 h post-mortem. p values for all statistical comparisons shown at bottom. A p value < 0.05 that is not bolded in red did not pass the Benjamini-Hochberg correction

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