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Fig. 5 | Clinical Epigenetics

Fig. 5

From: DNA methylation and histone post-translational modification stability in post-mortem brain tissue

Fig. 5

Immunohistochemical detection of histone 3 methylation PTMs (H3K4me3, H3K36me3) in neonatal pig neocortex. In control (0 h) brain, the nuclei of almost all cell types are positive except rare endothelial cells. Photomicrographs show that some large neurons (red arrows) have a minor decrease in intensity of immunoreactivity for H3K4me3 at 72 h. Images taken at × 400 magnification. DAB detection of antibody (brown) and hematoxylin counterstain (blue)

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