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Fig. 3 | Clinical Epigenetics

Fig. 3

From: DNA methylation and histone post-translational modification stability in post-mortem brain tissue

Fig. 3

Quantitation of histone epigenetic modifications on Western blots of neonatal pig brain. There were no differences between normoxic and hypoxic samples; therefore, all data were pooled (n = 7) and densitometric band “quantity” displayed (mean ± 95% confidence intervals). H3K4me3 and H3K27me3 remained stable ≥ 72 h post-mortem. H3K36me3 was stable for 24 h but decreased significantly by 48 h. H3panAc decreased at 24 h and was negligible by 48 h; the difference was not significant because the initial values were low with wide variation. H4K5ac and H4K12ac were significantly decreased by 48 h. p values significant at p < 0.05 that passed the Benjamini-Hochberg correction are shown on the graphs

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