Fig. 1

The effects of MPT0G211 on HL-60 and MOLT-4 cell growth and cell cycle progression. a Acetyl-α-tubulin and acetyl-histone 3 were detected in cells treated with MPT0G211 or tubastatin A (TBA) for 24 h. b HL-60, MOLT-4, and HUVECs were incubated with different concentrations of MPT0G211 or TBA for 48 h. Cell viability was evaluated using an MTT assay. c HL-60 and d MOLT-4 cells were treated with MPT0G211 or TBA for 48 h and analyzed by flow cytometry to assess cell cycle distribution. Data are shown as means ± standard errors of the means. *p < 0.05 versus the TBA-treated group