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Table 4 Top enriched canonical pathways by IPA

From: Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

Contrast

Pathway

p value

M10h vs M0

Unfolded protein response

8.82 × 10−3

Salvage Pathways of Pyrimidine Deoxyribonucleotides

0.021

Glycogen Degradation II

0.031

Glycogen Degradation III

0.036

Granzyme B Signalling

0.041

Gα12/13 Signalling

0.046

Lipid Antigen Presentation by CD1

0.048

M7d vs M0

S-Methyl-5-thio-α-d-ribose 1-phosphate Degradation

6.82 × 10−3

Gustation Pathway

0.025