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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer

Fig. 3

Snail2 regulates EMT in CRC cells. a Morphological changes associated with EMT as observed in phase contrast images of SW480-N, SW480-Snail2, SW620-N, and SW620-Sh-Snail2 cells. Phase contrast images were taken at × 10 magnification. b Expression of E-cadherin, fibronectin, vimentin, and Snail2 in SW480-N, SW480-Snail2, SW620-N, and SW620-Sh-Snail2 cells was analyzed by qPCR and shown as “relative mRNA levels.” Data represent the mean ± SD. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001. c Expression of E-cadherin, fibronectin, vimentin, and Snail2 in these cells was analyzed by western blotting

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