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Table 2 Epigenome-wide significant CpG sites for tobacco smoking in a veteran HIV-positive population: a meta-analysis

From: Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality

Probe

Chr

Position

Nearest gene

p dis

Effect (SE)dis

p rep

Effect (SE)rep

Z score

p meta

Direction

Hat p

cg05575921

5

373,378

AHRR

3.64E−40

− 0.134 (0.009)

1.36E−40

− 0.164 (0.011)

− 18.800

7.56E−79

–

0.480

cg21566642

2

233,284,661

 

1.35E−27

− 0.078 (0.007)

2.64E−36

− 0.096 (0.007)

− 16.543

1.81E−61

–

0.076

cg01940273

2

233,284,934

 

1.53E−26

− 0.056 (0.005)

6.92E−33

− 0.068 (0.005)

− 15.944

3.12E−57

–

0.144

cg23576855

5

373,299

AHRR

9.77E−31

− 0.117 (0.009)

3.67E−27

− 0.127 (0.011)

− 15.791

3.58E−56

–

0.975

cg26703534

5

377,358

AHRR

4.18E−21

− 0.034 (0.003)

2.50E−17

− 0.038 (0.004)

− 12.670

8.65E−37

–

0.811

cg21161138

5

399,360

AHRR

5.82E−18

− 0.034 (0.004)

8.62E−16

− 0.039 (0.005)

− 11.803

3.78E−32

–

0.994

cg09935388

1

92,947,588

GFI1

1.47E−13

− 0.059 (0.008)

1.61E−18

− 0.090 (0.010)

− 11.394

4.48E−30

–

0.167

cg03636183

19

17,000,585

F2RL3

2.42E−17

− 0.067 (0.008)

7.86E−12

− 0.056 (0.008)

− 10.861

1.76E−27

–

0.438

cg21322436

7

145,812,842

CNTNAP2

9.60E−14

− 0.024 (0.003)

6.16E−15

− 0.028 (0.003)

− 10.766

4.98E−27

–

0.532

cg03329539

2

233,283,329

 

1.29E−15

− 0.029 (0.003)

3.22E−12

− 0.030 (0.004)

− 10.600

3.00E−26

–

0.720

cg25648203

5

395,444

AHRR

7.14E−13

− 0.025 (0.003)

2.29E−13

− 0.033 (0.004)

− 10.248

1.20E−24

–

0.642

cg11660018

11

86,510,915

PRSS23

8.89E−11

− 0.024 (0.004)

1.02E−15

− 0.036 (0.004)

− 10.215

1.69E−24

–

0.148

cg23771366

11

86,510,998

PRSS23

4.21E−07

− 0.020 (0.004)

4.97E−20

− 0.042 (0.004)

− 9.951

2.50E−23

–

0.001

cg05284742

14

93,552,128

ITPK1

1.24E−13

− 0.018 (0.002)

3.22E−11

− 0.020 (0.003)

− 9.947

2.60E−23

–

0.839

cg19572487

17

38,476,024

RARA

1.82E−08

− 0.024 (0.004)

3.79E−17

− 0.040 (0.005)

− 9.858

6.30E−23

–

0.020

cg01901332

11

75,031,054

ARRB1

1.16E−14

− 0.031 (0.004)

8.50E−10

− 0.030 (0.005)

− 9.830

8.32E−23

–

0.436

cg24859433

6

30,720,203

 

4.20E−11

− 0.024 (0.004)

3.64E−13

− 0.032 (0.004)

− 9.782

1.35E−22

–

0.415

cg15342087

6

30,720,209

 

4.85E−11

− 0.023 (0.003)

6.14E−13

− 0.027 (0.004)

− 9.718

2.54E−22

–

0.437

cg03450842

10

80,834,947

ZMIZ1

6.08E−11

− 0.018 (0.003)

5.02E−13

− 0.026 (0.003)

− 9.712

2.69E−22

–

0.412

cg04551776

5

393,366

AHRR

7.00E−10

− 0.017 (0.003)

1.34E−13

− 0.029 (0.004)

− 9.558

1.20E−21

–

0.227

cg12803068

7

45,002,919

MYO1G

8.63E−10

0.047 (0.008)

5.40E−12

0.064 (0.009)

9.188

4.02E−20

++

0.391

cg15212295

17

64,710,687

PRKCA

6.36E−10

− 0.014 (0.002)

1.22E−10

− 0.021 (0.003)

− 8.911

5.07E−19

–

0.624

cg14753356

6

30,720,108

 

4.55E−09

− 0.018 (0.003)

6.42E−11

− 0.028 (0.004)

− 8.744

2.25E−18

–

0.436

cg25189904

1

68,299,493

GNG12

3.14E−06

− 0.035 (0.008)

7.95E−15

− 0.066 (0.008)

− 8.708

3.11E−18

–

0.012

cg02657160

3

98,311,063

CPOX

8.20E−10

− 0.014 (0.002)

7.79E−10

− 0.015 (0.002)

− 8.685

3.79E−18

–

0.758

cg13193840

2

233,285,289

 

1.62E−08

− 0.013 (0.002)

4.55E−11

− 0.021 (0.003)

− 8.622

6.58E−18

–

0.336

cg07986378

12

11,898,284

ETV6

1.54E−06

− 0.024 (0.005)

5.41E−13

− 0.040 (0.005)

− 8.435

3.30E−17

–

0.046

cg22851561

14

74,214,183

C14orf43

5.28E−10

− 0.019 (0.003)

1.17E−08

− 0.026 (0.004)

− 8.432

3.39E−17

–

0.948

cg27537125

1

25,349,681

 

1.45E−09

− 0.009 (0.002)

2.48E−08

− 0.010 (0.002)

− 8.226

1.93E−16

–

0.960

cg06644428

2

233,284,112

 

2.07E−06

− 0.016 (0.003)

8.58E−12

− 0.029 (0.004)

− 8.129

4.34E−16

–

0.079

cg14624207

11

68,142,198

LRP5

4.95E−09

− 0.015 (0.003)

2.13E−08

− 0.019 (0.003)

− 8.098

5.61E−16

–

0.915

cg26271591

2

178,125,956

NFE2L2

5.49E−06

− 0.025 (0.005)

3.90E−12

− 0.052 (0.007)

− 8.058

7.76E−16

–

0.048

cg11902777

5

368,843

AHRR

3.87E−10

− 0.012 (0.002)

5.52E−07

− 0.008 (0.002)

− 7.993

1.32E−15

–

0.543

cg19859270

3

98,251,294

GPR15

2.46E−10

− 0.013 (0.002)

1.21E−06

− 0.007 (0.001)

− 7.939

2.03E−15

–

0.443

cg08709672

1

206,224,334

AVPR1B

9.81E−09

− 0.021 (0.004)

8.12E−08

− 0.019 (0.004)

− 7.852

4.09E−15

–

0.991

cg23916896

5

368,804

AHRR

1.14E−11

− 0.040 (0.006)

2.89E−05

− 0.019 (0.004)

− 7.816

5.45E−15

–

0.116

cg19089201

7

45,002,287

MYO1G

7.39E−08

0.027 (0.005)

2.09E−08

0.042 (0.007)

7.758

8.63E−15

++

0.669

cg02583484

12

54,677,008

HNRNPA1

2.94E−06

− 0.013 (0.003)

3.50E−10

− 0.023 (0.004)

− 7.699

1.37E−14

–

0.162

cg09022230

7

5,457,225

TNRC18

1.45E−07

− 0.019 (0.004)

2.52E−08

− 0.027 (0.005)

− 7.646

2.07E−14

–

0.626

cg07178945

12

4,488,800

FGF23

1.87E−07

0.020 (0.004)

2.08E−08

0.028 (0.005)

7.635

2.27E−14

++

0.587

cg04885881

1

11,123,118

 

1.46E−06

− 0.025 (0.005)

1.79E−09

− 0.034 (0.006)

− 7.626

2.43E−14

–

0.265

cg25949550

7

145,814,306

CNTNAP2

1.21E−08

− 0.011 (0.002)

4.80E−07

− 0.013 (0.002)

− 7.601

2.94E−14

–

0.837

cg00073090

19

1,265,879

 

1.20E−05

− 0.011 (0.002)

1.97E−10

− 0.017 (0.003)

− 7.542

4.63E−14

–

0.095

cg27241845

2

233,250,370

 

2.53E−06

− 0.019 (0.004)

1.98E−08

− 0.034 (0.006)

− 7.270

3.59E−13

–

0.371

cg18900812

6

36,646,127

CDKN1A

4.74E−06

− 0.017 (0.004)

9.22E−09

− 0.021 (0.004)

− 7.265

3.74E−13

–

0.280

cg15159987

19

17,003,890

CPAMD8

8.33E−10

− 0.019 (0.003)

1.11E−04

− 0.014 (0.004)

− 7.125

1.04E−12

–

0.174

cg19254163

11

60,623,782

GPR44

6.38E−07

− 0.012 (0.002)

1.02E−06

− 0.019 (0.004)

− 6.975

3.06E−12

–

0.859

cg08149865

8

21,914,600

EPB49

1.23E−06

− 0.014 (0.003)

9.45E−07

− 0.016 (0.003)

− 6.891

5.53E−12

–

0.782

cg20295214

1

206,226,794

AVPR1B

1.47E−06

− 0.014 (0.003)

9.65E−07

− 0.011 (0.002)

− 6.863

6.76E−12

–

0.766

cg23219570

12

4,488,893

FGF23

1.30E−05

0.012 (0.003)

8.52E−08

0.019 (0.004)

6.842

7.83E−12

++

0.346

cg26529655

5

424,371

AHRR

2.39E−06

− 0.011 (0.002)

7.37E−07

− 0.012 (0.002)

− 6.827

8.68E−12

–

0.687

cg11554391

5

321,320

AHRR

6.57E−06

− 0.012 (0.003)

2.79E−07

− 0.015 (0.003)

− 6.800

1.05E−11

–

0.495

cg25305703

8

128,378,218

 

1.26E−04

− 0.020 (0.005)

6.37E−09

− 0.037 (0.006)

− 6.765

1.34E−11

–

0.103

cg09099830

16

30,485,485

ITGAL

1.42E−06

− 0.015 (0.003)

2.15E−06

− 0.017 (0.003)

− 6.759

1.39E−11

–

0.860

cg10750182

10

73,497,514

CDH23

1.23E−07

− 0.012 (0.002)

2.98E−05

− 0.011 (0.003)

− 6.715

1.88E−11

–

0.579

cg14580211

5

150,161,299

C5orf62

1.05E−05

− 0.020 (0.004)

3.19E−07

− 0.030 (0.006)

− 6.709

1.96E−11

–

0.464

cg04180046

7

45,002,736

MYO1G

2.39E−05

0.027 (0.006)

1.35E−07

0.045 (0.008)

6.686

2.30E−11

++

0.330

cg17287155

5

393,347

AHRR

1.43E−05

− 0.010 (0.002)

3.74E−07

− 0.011 (0.002)

− 6.639

3.15E−11

–

0.450

cg14316231

8

41,895,100

MYST3

2.32E−05

− 0.012 (0.003)

2.87E−07

− 0.026 (0.005)

− 6.595

4.26E−11

–

0.386

cg03604011

5

400,201

AHRR

1.38E−07

0.012 (0.002)

7.92E−05

0.005 (0.001)

6.544

5.98E−11

++

0.479

cg09662411

1

92,946,132

GFI1

3.82E−05

− 0.025 (0.006)

3.56E−07

− 0.038 (0.007)

− 6.484

8.93E−11

–

0.361

cg24996979

14

74,223,355

C14orf43

1.17E−04

− 0.009 (0.002)

1.20E−07

− 0.015 (0.003)

− 6.428

1.29E−10

–

0.214

cg13751113

11

118,085,214

AMICA1

8.66E−06

− 0.011 (0.003)

5.27E−06

− 0.015 (0.003)

− 6.359

2.03E−10

–

0.767

cg00310412

15

74,724,918

SEMA7A

3.66E−04

− 0.011 (0.003)

4.49E−08

− 0.020 (0.004)

− 6.337

2.34E−10

–

0.117

cg18642234

3

49,394,622

GPX1

1.24E−06

− 0.013 (0.003)

4.44E−05

− 0.012 (0.003)

− 6.331

2.43E−10

–

0.748

cg26361535

8

144,576,604

ZC3H3

9.58E−04

− 0.014 (0.004)

1.10E−08

− 0.029 (0.005)

− 6.313

2.74E−10

–

0.054

cg00295485

2

106,755,721

UXS1

5.86E−05

− 0.017 (0.004)

7.63E−07

− 0.029 (0.006)

− 6.311

2.77E−10

–

0.382

cg03440944

7

45,023,329

C7orf40

8.68E−08

− 0.012 (0.002)

4.66E−04

− 0.013 (0.004)

− 6.301

2.96E−10

–

0.275

cg12075928

8

141,801,307

PTK2

4.90E−06

− 0.021 (0.005)

1.60E−05

− 0.026 (0.006)

− 6.284

3.30E−10

–

0.969

cg01481251

11

32,912,719

 

5.67E−05

− 0.016 (0.004)

1.05E−06

− 0.012 (0.002)

− 6.274

3.51E−10

–

0.410

cg03707168

19

49,379,127

PPP1R15A

1.16E−05

− 0.024 (0.006)

6.89E−06

− 0.027 (0.006)

− 6.274

3.52E−10

–

0.766

cg11436113

20

19,191,145

 

1.29E−05

− 0.014 (0.003)

6.14E−06

− 0.018 (0.004)

− 6.274

3.53E−10

–

0.741

cg00706683

2

233,251,030

ECEL1P2

7.54E−08

0.020 (0.004)

6.22E−04

0.016 (0.005)

6.267

3.69E−10

++

0.244

cg10062919

17

38,503,802

RARA

3.21E−05

− 0.008 (0.002)

2.37E−06

− 0.009 (0.002)

− 6.259

3.86E−10

–

0.539

cg06394460

13

28,130,393

LNX2

8.32E−07

− 0.028 (0.006)

1.36E−04

− 0.019 (0.005)

− 6.206

5.44E−10

–

0.568

cg04517079

6

41,546,161

FOXP4

1.28E−04

− 0.010 (0.002)

6.03E−07

− 0.014 (0.003)

− 6.205

5.48E−10

–

0.300

cg16547579

20

4,954,333

SLC23A2

3.74E−04

− 0.011 (0.003)

1.39E−07

− 0.019 (0.004)

− 6.194

5.87E−10

–

0.154

cg21446172

1

223,745,234

CAPN8

1.76E−04

− 0.010 (0.003)

4.68E−07

− 0.020 (0.004)

− 6.180

6.40E−10

–

0.260

cg07251887

17

73,641,809

RECQL5

1.03E−07

− 0.016 (0.003)

8.91E−04

− 0.013 (0.004)

− 6.158

7.38E−10

–

0.230

cg15474579

6

36,645,812

CDKN1A

1.01E−05

− 0.013 (0.003)

2.32E−05

− 0.018 (0.004)

− 6.115

9.66E−10

–

0.934

cg16398761

14

74,220,238

C14orf43

1.58E−05

− 0.010 (0.002)

2.13E−05

− 0.013 (0.003)

− 6.056

1.39E−09

–

0.870

cg13039251

5

32,018,601

PDZD2

4.03E−03

0.014 (0.005)

8.21E−09

0.040 (0.007)

6.035

1.59E−09

++

0.024

cg23110422

21

40,182,073

ETS2

5.94E−05

− 0.015 (0.004)

5.59E−06

− 0.020 (0.004)

− 6.034

1.60E−09

–

0.560

cg02275418

3

15,372,726

SH3BP5

5.16E−05

− 0.009 (0.002)

7.61E−06

− 0.008 (0.002)

− 6.013

1.82E−09

–

0.609

cg03188382

2

233,245,886

ALPP

3.42E−08

− 0.021 (0.004)

3.83E−03

− 0.012 (0.004)

− 6.008

1.88E−09

–

0.099

cg14712058

19

16,988,083

SIN3B

1.93E−07

− 0.018 (0.003)

1.37E−03

− 0.012 (0.004)

− 5.990

2.09E−09

–

0.226

cg03109660

4

37,684,505

RELL1

4.91E−06

− 0.013 (0.003)

1.05E−04

− 0.018 (0.005)

− 5.987

2.14E−09

–

0.780

cg08035323

2

9,843,525

 

1.19E−03

0.017 (0.005)

1.31E−07

0.036 (0.007)

5.970

2.37E−09

++

0.099

cg13038618

14

77,467,391

 

1.08E−03

− 0.011 (0.003)

1.54E−07

− 0.020 (0.004)

− 5.970

2.38E−09

–

0.108

cg03234777

11

118,095,544

AMICA1

4.97E−05

− 0.009 (0.002)

1.34E−05

− 0.011 (0.002)

− 5.936

2.92E−09

–

0.677

cg13422817

12

4,550,927

FGF6

1.02E−05

0.011 (0.003)

7.28E−05

0.013 (0.003)

5.933

2.98E−09

++

0.913

cg15657641

11

47,939,769

 

1.73E−06

0.008 (0.002)

3.77E−04

0.007 (0.002)

5.923

3.17E−09

++

0.508

cg24851513

3

52,099,522

C3orf74

1.44E−04

0.007 (0.002)

4.37E−06

0.007 (0.002)

5.913

3.37E−09

++

0.444

cg17485141

2

42,566,556

 

8.57E−04

0.005 (0.002)

4.17E−07

0.014 (0.003)

5.890

3.86E−09

++

0.154

cg00385142

3

98,235,918

CLDND1

2.87E−07

− 0.009 (0.002)

1.81E−03

− 0.004 (0.001)

− 5.881

4.09E−09

–

0.223

cg26764244

1

68,299,511

GNG12

1.68E−03

− 0.014 (0.004)

1.52E−07

− 0.026 (0.005)

− 5.878

4.14E−09

–

0.090

cg01899089

5

369,969

AHRR

4.09E−08

− 0.016 (0.003)

6.94E−03

− 0.011 (0.004)

− 5.854

4.80E−09

–

0.077

cg25013095

2

231,809,672

 

3.75E−08

− 0.008 (0.001)

7.93E−03

− 0.002 (0.001)

− 5.835

5.39E−09

–

0.070

cg25292882

15

39,431,467

 

1.72E−04

− 0.011 (0.003)

6.24E−06

− 0.009 (0.002)

− 5.829

5.57E−09

–

0.459

cg14179389

1

92,947,961

GFI1

6.93E−03

− 0.013 (0.005)

1.63E−08

− 0.033 (0.006)

− 5.827

5.66E−09

–

0.022

cg09837977

7

110,731,201

LRRN3

8.75E−06

− 0.008 (0.002)

1.92E−04

− 0.006 (0.002)

− 5.795

6.84E−09

–

0.760

cg16503724

3

17,130,667

PLCL2

2.95E−03

0.007 (0.002)

1.19E−07

0.020 (0.004)

5.786

7.22E−09

++

0.065

cg20454518

12

133,135,463

FBRSL1

2.88E−04

0.021 (0.006)

6.45E−06

0.028 (0.006)

5.728

1.01E−08

++

0.409

cg16382047

2

231,790,037

GPR55

6.89E−06

− 0.018 (0.004)

3.70E−04

− 0.023 (0.006)

− 5.717

1.08E−08

–

0.643

cg06972908

16

30,488,321

ITGAL

1.26E−05

− 0.009 (0.002)

2.17E−04

− 0.013 (0.003)

− 5.716

1.09E−08

–

0.784

cg00605777

2

97,533,635

SEMA4C

1.29E−05

− 0.009 (0.002)

2.47E−04

− 0.009 (0.003)

− 5.690

1.27E−08

–

0.768

cg00300637

5

319,433

AHRR

9.94E−04

0.012 (0.004)

1.84E−06

0.021 (0.004)

5.661

1.50E−08

++

0.214

cg01882991

6

6,677,756

 

5.00E−05

− 0.010 (0.002)

8.16E−05

− 0.013 (0.003)

− 5.653

1.58E−08

–

0.909

cg05049335

11

66,103,889

RIN1

4.95E−07

− 0.008 (0.002)

4.26E−03

− 0.007 (0.002)

− 5.627

1.84E−08

–

0.180

cg10788371

11

76,381,040

LRRC32

6.06E−02

− 0.006 (0.003)

5.69E−10

− 0.024 (0.004)

− 5.600

2.14E−08

–

0.001

cg04716530

16

30,485,684

ITGAL

3.32E−05

− 0.006 (0.002)

1.78E−04

− 0.009 (0.002)

− 5.592

2.25E−08

–

0.928

cg09006487

3

72,424,982

RYBP

2.93E−09

− 0.023 (0.004)

6.83E−02

− 0.009 (0.005)

− 5.584

2.35E−08

–

0.007

cg10841124

5

433,274

AHRR

2.42E−05

0.007 (0.002)

2.63E−04

0.013 (0.004)

5.577

2.45E−08

++

0.833

cg01956154

14

94,423,399

ASB2

3.59E−05

− 0.009 (0.002)

1.81E−04

− 0.009 (0.002)

− 5.576

2.46E−08

–

0.936

cg26800893

11

67,184,596

ATPGD1

5.39E−05

0.008 (0.002)

1.21E−04

0.008 (0.002)

5.575

2.48E−08

++

0.955

cg05460226

17

8,804,279

PIK3R5

2.57E−−04

− 0.015 (0.004)

2.13E−05

− 0.029 (0.007)

− 5.572

2.51E−08

–

0.538

cg18146737

1

92,946,700

GFI1

1.99E−04

− 0.036 (0.010)

3.50E−05

− 0.037 (0.009)

− 5.543

2.97E−08

–

0.625

cg16201146

20

19,191,526

 

4.06E−07

− 0.012 (0.002)

7.10E−03

− 0.009 (0.003)

− 5.541

3.01E−08

–

0.137

cg16814719

8

134,114,834

TG;SLA

4.48E−06

− 0.005 (0.001)

1.41E−03

− 0.005 (0.002)

− 5.533

3.16E−08

–

0.427

cg00501876

3

39,193,251

CSRNP1

5.22E−04

− 0.009 (0.003)

1.15E−05

− 0.014 (0.003)

− 5.529

3.22E−08

–

0.400

cg08763102

4

3,079,751

HTT

1.73E−03

− 0.007 (0.002)

2.13E−06

− 0.015 (0.003)

− 5.525

3.30E−08

–

0.184

cg07381806

19

2,094,327

MOBKL2A

1.68E−03

− 0.015 (0.005)

2.62E−06

− 0.035 (0.007)

− 5.502

3.75E−08

–

0.196

cg01731783

14

74,211,788

C14orf43

8.41E−07

− 0.008 (0.002)

5.40E−03

− 0.006 (0.002)

− 5.500

3.81E−08

–

0.185

cg19717773

7

2,847,554

GNA12

1.86E−04

− 0.033 (0.009)

5.57E−05

− 0.043 (0.011)

− 5.482

4.21E−08

–

0.691

cg17791651

1

38,513,489

POU3F1

4.05E−05

− 0.011 (0.003)

2.99E−04

− 0.012 (0.003)

− 5.468

4.55E−08

–

0.876

cg23161492

15

90,357,202

ANPEP

6.62E−04

− 0.016 (0.005)

1.30E−05

− 0.026 (0.006)

− 5.464

4.66E−08

–

0.387

cg07465627

17

53,167,407

STXBP4

3.03E−06

− 0.011 (0.002)

2.99E−03

− 0.013 (0.004)

− 5.439

5.36E−08

–

0.311

cg16702313

14

74,251,926

C14orf43

4.78E−04

− 0.007 (0.002)

2.64E−05

− 0.008 (0.002)

− 5.421

5.94E−08

–

0.490

cg07339236

20

50,312,490

ATP9A

5.74E−03

− 0.007 (0.003)

6.65E−07

− 0.014 (0.003)

− 5.411

6.27E−08

–

0.080

cg15187398

19

2,093,896

MOBKL2A

2.94E−03

− 0.011 (0.004)

2.10E−06

− 0.019 (0.004)

− 5.410

6.29E−08

–

0.150

cg02743070

10

80,834,309

ZMIZ1

7.44E−05

− 0.007 (0.002)

2.35E−04

− 0.009 (0.002)

− 5.406

6.45E−08

–

0.990

cg20059928

15

40,361,485

 

4.01E−05

− 0.025 (0.006)

5.01E−04

− 0.021 (0.006)

− 5.377

7.57E−08

–

0.798

cg14120703

9

139,416,102

NOTCH1

4.33E−05

− 0.008 (0.002)

4.80E−04

− 0.008 (0.002)

− 5.372

7.79E−08

–

0.814

cg11816838

3

150,484,093

 

1.33E−02

− 0.006 (0.002)

1.81E−07

− 0.009 (0.002)

− 5.369

7.90E−08

–

0.033

cg26057754

1

183,774,231

RGL1

6.85E−06

− 0.004 (0.001)

2.32E−03

− 0.003 (0.001)

− 5.367

8.01E−08

–

0.400

cg19713851

2

233,246,594

ALPP

5.33E−05

− 0.031 (0.008)

4.12E−04

− 0.032 (0.009)

− 5.364

8.13E−08

–

0.863

cg03519879

14

74,227,499

C14orf43

8.89E−07

− 0.008 (0.002)

9.74E−03

− 0.006 (0.002)

− 5.357

8.46E−08

–

0.144

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Clinical Epigenetics

ISSN: 1868-7083

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