Table 1 Changes in mtDNA methylation resulting from different mtDNA genotypes
From: The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma
Location of C | Strand | Annotation | 143BGBM vs. 143B143B | 143BNSC vs. 143B143B | 143BNSC vs. 143BGBM | ||||
|---|---|---|---|---|---|---|---|---|---|
Early tumors | 498 | + | Non-coding | * | 19.83% | ||||
9143 | + | ATP6 | * | 5.85% | |||||
13,209 | – | ND5 | ** | − 7.00% | *** | 7.54% | |||
14,758 | + | CYTB | ** | 15.75% | ** | 12.46% | |||
14,802 | + | CYTB | ** | 12.04% | ** | 19.64% | |||
14,829 | + | CYTB | ** | 7.20% | |||||
Late tumors | 3695 | + | ND1 | ** | − 1.69% | ** | 10.58% | ||
3705 | + | ND1 | *** | − 7.57% | ** | 5.11% | |||
13,712 | + | ND5 | * | 7.31% | |||||