Fig. 2

Integration of gene expression and metabolomics networks into the epigenetic fingerprint loci. Black diamonds represent epigenetic loci, blue rectangles represent metabolites, and purple ellipses represent genes. Red edges indicate negative associations/correlations and green positive. Thicker edges represent the 12 FDR significant metabolite–gene expression correlations. For improved visualization all metabolite-gene expression associations with P < 0.001 are represented