Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Table 1 Pearson correlations between high- and low-sensitivity CRP measures and imputed immune cell profiles

	Wave 1		Wave 2		Wave 3		Wave 4
	ls	hs	ls	hs	ls	hs	ls	hs
Total CD8+T	−0.077	NA	− 0.057	−0.041	− 0.053	−0.053	− 0.098	NA
Total CD4+T	−0.167	NA	−0.104	−0.107	− 0.12	−0.112	− 0.079	NA
Natural killer	−0.108	NA	−0.067	−0.086	− 0.094	−0.083	− 0.15	NA
B cells	−0.093	NA	−0.053	−0.029	− 0.084	−0.071	0.006	NA
Senescent CD8+T	0.119	NA	0.077	0.072	0.039	0.044	0.003	NA
Naïve CD8+T	−0.068	NA	−0.055	−0.054	0.089	0.071	−0.102	NA
Naïve CD4+T	−0.066	NA	−0.024	−0.022	0.01	0.015	−0.033	NA
Monocytes	0.037	NA	0.099	0.101	0.079	0.087	0.134	NA
Granulocytes	0.192	NA	0.106	0.097	0.146	0.119	0.112	NA
Plasmablasts	0.186	NA	0.133	0.127	0.132	0.119	0.103	NA

ISSN: 1868-7083