Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis

Table 1 Subject characteristics

Patient number	Status	Age	Sex	Genotype	FEV₁ (%)	Microbiology	Antibiotic and/or modulator therapy
1	CF	18	Male	F508del/Y1092X	77	S. aureus many mixed	None
2	CF	24	Male	F508del/F508del	96	S. aureus	Aztreonam, colistimethate, doxycycline, ivacaftor/lumacaftor
3	CF	28	Female	F508del/F508del	91	A. xylosoxidans moderate mixed	Colistimethate, tobramycin
4	CF	18	Female	F508del/F508del	88	S. aureus many mixed A. xylosoxidans, moderate mixed	Colistimethate, tobramycin, ivacaftor/lumacaftor
5	Healthy	26	Female
6	Healthy	33	Male
7	Healthy	25	Female
8	Healthy	20	Female

ISSN: 1868-7083