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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma

Fig. 3

Demethylation assays in thyroid cancer cell lines (TPC1 and BCPAP). a Pyrogram showing the percentage of basal methylation of MIR21 (unmethylated in both cell lines) and MIR146B (> 50% methylation in both cell lines). b The demethylation in the mapped region of MIR146B was demonstrated after 5-Aza-dC treatment in TPC1 and BCPAP cell lines. BCPAP cell line had no changes in hsa-miR-146b-5p expression and TPC1 cell line presented seven-fold increased expression levels after the induced demethylation

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Clinical Epigenetics

ISSN: 1868-7083

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