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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome

Fig. 1

Adiponectin mRNA levels in adipose tissues of women with NGT vs. GDM and their relations to plasma adiponectin. Gene expression of adiponectin (ADIPOQ) normalized to peptidylprolyl isomerase A (PPIA) analyzed in subcutaneous (SAT) and visceral adipose tissues (VAT), respectively, of normal glucose tolerance women (NGT; open bars; n = 30) vs. women with gestational diabetes mellitus (GDM; red bars; n = 22–25). Sum of expression of both fat depots (SAT+VAT) is plotted additionally (ab). Data are means ± SEM, shown as raw data (a) or percentage of NGT levels (b). Pearson’s correlation coefficients (R) calculating the relationship between maternal blood (MB) adiponectin levels and adipose tissue gene expression data (ce). NGT, open circles; GDM, red circles. AU, arbitrary units. *P < 0.05, **P < 0.01

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